Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
sn-glycerol-3-kinase
Overview
Common Variants in the Glycerol Kinase Gene Reduce Tuberculosis Drug Efficacy.
Frameshift mutations in the glpK gene, which encodes the glycerol-3-kinase, are associated with reduced susceptibility to pyrazinamide in Mycobacterium tuberculosis.
Chemical interplay and complementary adaptative strategies toggle bacterial antagonism and co-existence.
The study identifies mutations in the fusA gene of Pseudomonas chlororaphis PCL1606 that confer resistance to bacillaene, a bacteriostatic compound produced by Bacillus amyloliquefaciens FZB42. Additionally, mutations in the glpK gene of B. amyloliquefaciens FZB42 lead to pleiotropic cellular changes and increased antibiotic resistance.
Whole Genome Sequencing Identifies Novel Mutations Associated With Bedaquiline Resistance in Mycobacterium tuberculosis.
Mutations in rv0678 and a novel gene glpK were identified as contributing to bedaquiline resistance in Mycobacterium tuberculosis.
Genetic determinants of Mycobacterium tuberculosis adaptation and drug efficacy during stationary phase growth.
The study identifies genes involved in Mycobacterium tuberculosis adaptation to stationary phase and drug efficacy, highlighting the role of lipid metabolism and specific genes like katG, rv1339, glpK, mce4, and pssA in drug resistance and tolerance.
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