gluP

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efflux pump

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

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UniProt

Protein entries specific to gluP

AMR Rules

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Validation StatusCandidate

Overview

Mechanism: upregulates efflux pump Hp1174 (gluP)
Validation Method: qRT-PCR and MIC testing
Drug Classes: ampicillin, penicillin, amoxicillin, tetracycline, metronidazole, furazolidone
Organisms: Helicobacter pylori
Papers: 1
Databases: Reslit

Papers1

Bifunctional Enzyme SpoT Is Involved in Biofilm Formation of Helicobacter pylori with Multidrug Resistance by Upregulating Efflux Pump Hp1174 (gluP).

PMID 30181372 · 2018

The study identifies gluP as an efflux pump involved in biofilm formation and multidrug resistance in Helicobacter pylori, showing that its expression is upregulated by SpoT.

Gene Information

Gene Name: gluP
Allele: gluP
Encodes: efflux pump
Source Database: Reslit
Mechanism: upregulates efflux pump Hp1174 (gluP)
Confers Resistance To: ampicillinpenicillinamoxicillintetracyclinemetronidazolefurazolidone
Organisms Tested In: • Helicobacter pylori
Validation Method: qRT-PCR and MIC testing

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gluP

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gluP

Gene Information