graF

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hypothetical protein (contains bipartite nuclear targeting sequence)

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Validation StatusCandidate

Overview

Validation Method: overexpression in N315 leading to increased MICs
Drug Classes: vancomycin, teicoplanin, oxacillin
Organisms: Staphylococcus aureus
Papers: 1
Databases: Reslit

Papers1

DNA microarray-based identification of genes associated with glycopeptide resistance in Staphylococcus aureus.

PMID 16048954 · 2005

The study identifies 17 genes associated with glycopeptide resistance in Staphylococcus aureus, including 8 novel genes. Overexpression of these genes, particularly graF and msrA2, significantly increases resistance to vancomycin, teicoplanin, and oxacillin.

Gene Information

Gene Name: graF
Allele: graF
Encodes: hypothetical protein (contains bipartite nuclear targeting sequence)
Source Database: Reslit
Confers Resistance To: vancomycinteicoplaninoxacillin
Organisms Tested In: • Staphylococcus aureus
Validation Method: overexpression in N315 leading to increased MICs

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graF

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graF

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