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Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
two-component sensor histidine kinase
Overview
| Candidate |
| F38G | - | The F38G mutation reduces the ability of GraS to sense and respond to cationic antimicrobial peptides, leading to decreased resistance to polymyxin B. | Staphylococcus aureus | Polymyxin b | Reslit | Candidate |
| T224I | - | - | - | Teicoplanin | Reslit | Candidate |
| L26F | - | - | - | Teicoplanin | Reslit | Candidate |
| I59L | - | - | - | Teicoplanin | Reslit | Candidate |
| T224K | - | - | - | Teicoplanin | Reslit | Candidate |
| T24K | - | - | - | Teicoplanin | Reslit | Candidate |
| S52N | - | - | Staphylococcus aureus | Daptomycin | Reslit | Candidate |
Genomic analysis reveals a point mutation in the two-component sensor gene graS that leads to intermediate vancomycin resistance in clinical Staphylococcus aureus.
A point mutation in the two-component sensor gene graS (T136I) was identified as a major contributor to intermediate vancomycin resistance in clinical Staphylococcus aureus.
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