iutA

aerobactin receptor

Validation StatusCandidate

Overview

Mechanism: enhances iron acquisition
Validation Method: plasmid sequencing and virulence testing
Drug Classes: Fluoroquinolone, Cephalosporins, Aminoglycoside, Polymyxin, Fosfomycin, Doxycycline, Florfenicol, Trimethoprim/sulfamethoxazole
Organisms: Klebsiella pneumoniae, Escherichia coli
Geographic Location: China|Taiwan, Northern Palestinian territories|Northern Palestine
Papers: 2
Databases: Reslit

Papers2

Molecular characterization of carbapenem-resistant and virulent plasmids in Klebsiella pneumoniae from patients with bloodstream infections in China.

PMID 33739229 · 2021

The study identifies the role of IS Kpn26 insertion in the acrR gene leading to multidrug resistance in ST11- bla KPC-2 Klebsiella pneumoniae. It also characterizes novel MDR-virulent plasmids carrying virulence factors and multiple antibiotic resistance genes.

Gene Information

Gene Name: iutA
Allele: iutA
Encodes: aerobactin receptor
Source Database: Reslit
Mechanism: enhances iron acquisition
Organisms Tested In: • Klebsiella pneumoniae
Geographic Location: China|Taiwan
Validation Method: plasmid sequencing and virulence testing
Sequence Accession: MT269819|MT269820|MT269821|MT269822|MT269823|MT269824|MT269825|MT269826|MT269827|MT269828|MT269829|MT269830|MT269831|MT269832|MT269833|MT269834|MT269835|MT269836|MT269837|MT269838|MT269839|MT269840|MT269841|MT269842|MT269843|MT269844|MT269845|MT269846|MT269847|MT269848|MT269849|MT269850|MT269851|MT269852

Molecular characterization of avian pathogenic Escherichia coli isolates from broiler farms in Northern Palestinian territories.

PMID 39897376 · 2024

The study identified several virulence genes, including iroN, hlyF, iutA, tsh, iss, ompT, papGI, papGII, papC, and cva/cvi, which were associated with antibiotic resistance in APEC isolates from broiler farms in Northern Palestine. These genes were found to be prevalent among the isolates and correlated with resistance to multiple antibiotics.

Gene Information

Gene Name: iutA
Allele: iutA
Encodes: ferric aerobactin receptor gene; iron transport (iron acquisition)
Source Database: Reslit
Confers Resistance To: FluoroquinoloneCephalosporinsAminoglycosidePolymyxinFosfomycinDoxycyclineFlorfenicolTrimethoprim/sulfamethoxazole
Organisms Tested In: • Escherichia coli
Geographic Location: Northern Palestinian territories|Northern Palestine
Validation Method: multiplex PCR

Comments (0)

No comments yet. Be the first to comment!

Browse AMR Genes

iutA

Gene Information

Gene Information