Browse AMR Genes

Explore antimicrobial resistance genes from the literature

lasR

transcriptional regulator

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to lasR

Browse AMR rules for lasR

Validation StatusCandidate

Overview

Mechanism: loss of function
Validation Method: mutation frequency analysis and complementation
Drug Classes: Beta-lactams, Ciprofloxacin|Ceftazidime|Meropenem, Ceftazidime/avibactam|Imipenem/relebactam|Meropenem/vaborbactam, Beta-lactam, Polymyxin
Organisms: Pseudomonas aeruginosa
Papers: 4
Databases: Reslit
Mutations: 7

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
A140D	-	-	-	Ciprofloxacin\|Ceftazidime\|Meropenem	Reslit	Candidate
A206V	-	-	-	Ciprofloxacin\|Ceftazidime\|Meropenem	Reslit	Candidate
93del	-	-	Pseudomonas aeruginosa	Ceftazidime/avibactam\|Imipenem/relebactam\|Meropenem/vaborbactam