Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
efflux pump
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| lde | Reslit | 7 | Fluoroquinolone, Ethidium bromide +2 | Listeria monocytogenes | Europe, Uruguay, Northeastern Ohio, the United States|Northeastern Ohio | 2003, 2006, 2016, 2018, 2020, 2021 | AL591824 | - |
| Lde |
| 2 |
| Fluoroquinolone, Ciprofloxacin |
| Listeria monocytogenes |
| Poland |
| 2009, 2022 |
| - |
| - |
Efflux pump Lde is associated with fluoroquinolone resistance in Listeria monocytogenes.
The lde gene encodes an efflux pump associated with fluoroquinolone resistance in Listeria monocytogenes.
Role of efflux pumps in adaptation and resistance of Listeria monocytogenes to benzalkonium chloride.
The study identified the efflux pumps MdrL and Lde in Listeria monocytogenes, demonstrating their roles in resistance to benzalkonium chloride and other antimicrobials. MdrL was found to be significantly upregulated upon adaptation to benzalkonium chloride, suggesting its involvement in the adaptation process.
Efflux-mediated drug resistance in bacteria: an update.
The paper provides an updated overview of drug efflux pumps in bacteria, focusing on their structure, mechanisms, and roles in multidrug resistance. It highlights the importance of RND, MFS, MATE, SMR, and ABC transporters in efflux-mediated resistance.
Resistance to Biocides in Listeria monocytogenes Collected in Meat-Processing Environments.
The study identifies the non-specific efflux pumps lde and mdrL as contributing to benzalkonium chloride resistance in Listeria monocytogenes strains isolated from meat-processing environments.
Role of Efflux Pumps in the in vitro Development of Ciprofloxacin Resistance in Listeria monocytogenes.
The efflux pump Lde contributes to ciprofloxacin resistance in Listeria monocytogenes by reducing ciprofloxacin accumulation.
Effect of Benzalkonium Chloride Adaptation on Sensitivity to Antimicrobial Agents and Tolerance to Environmental Stresses in Listeria monocytogenes.
The study identified the efflux pump gene mdrL as being involved in benzalkonium chloride (BC) adaptation in Listeria monocytogenes. The expression of mdrL was significantly upregulated in BC-adapted strains, and its deletion impaired growth in the presence of BC.
Does Shiga Toxin-Producing Escherichia coli and Listeria monocytogenes Contribute Significantly to the Burden of Antimicrobial Resistance in Uruguay?
The study identified several antimicrobial resistance genes in Shiga toxin-producing Escherichia coli (STEC) and Listeria monocytogenes isolates, including aph(3")-Ib, aph(3′)-Ia, aph(6)-Id, blaTEM-1B, sul2, tet(A), fosX, lin, norB, lde, mdrL, and fepA. These genes conferred resistance to various antibiotics such as ampicillin, trimethoprim-sulfamethoxazole, tetracycline, fosfomycin, lincomycin, ciprofloxacin, and erythromycin.
Prevalence and Antimicrobial Resistance Profiles of Foodborne Pathogens Isolated from Dairy Cattle and Poultry Manure Amended Farms in Northeastern Ohio, the United States.
The study identified several antimicrobial resistance genes in foodborne pathogens isolated from dairy cattle and poultry manure amended farms in Northeastern Ohio, including mphA, aadA, aphA1, tetA, aac(3)-IV, sulII, blaTEM, tetB, strA, aac(3)-Iva, ampC, lde, ermB, tet(O), aadB, penA, blaOXA-61, aadE, and aph-3-1.
Antimicrobial Resistance and Virulence Characterization of Listeria monocytogenes Strains Isolated from Food and Food Processing Environments.
The study identified several AMR genes in L. monocytogenes strains, including Lde, aadB, aac(3)-IIa(aacC2), sulI, sulII, lnuA, lnuB, and mefA, which confer resistance to ciprofloxacin, gentamicin, trimethoprim-sulfamethoxazole, and clindamycin.
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