lmo0919

ATP-binding cassette (ABC) transporter

Validation StatusCandidate

Overview

Validation Method: cloning in staphylococci and MIC testing
Drug Classes: streptogramin a (sga), lincosamides
Organisms: Staphylococcus aureus, Staphylococcus epidermidis
Papers: 1
Databases: Reslit

Papers1

Molecular analysis of resistance to streptogramin A compounds conferred by the Vga proteins of staphylococci.

PMID 15728891 · 2005

The study identifies and characterizes the Vga proteins, including vga(A), vga(A)v, vga(B), and Lmo0919, as conferring resistance to streptogramin A (SGA) and lincosamides in staphylococci. It also shows that vga(B) increases resistance to pristinamycin, a combination of SGA and SGB.

Gene Information

Gene Name: lmo0919
Allele: lmo0919
Encodes: ATP-binding cassette (ABC) transporter
Source Database: Reslit
Confers Resistance To: streptogramin a (sga)lincosamides
Organisms Tested In: • Staphylococcus aureus
• Staphylococcus epidermidis
Validation Method: cloning in staphylococci and MIC testing

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lmo0919

Gene Information