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Explore antimicrobial resistance genes from the literature
lincomycin exporter
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| Q52P | - | single resistance variant | Streptomyces lincolnensis | - | Card Database | Established |
| - | enhanced expression of lmrAB and yxaGH, resulting in multidrug resistance | Bacillus subtilis, Escherichia coli | Lincomycin | Reslit | Candidate |
Dissemination of antibiotic resistance genes from antibiotic producers to pathogens.
The study provides evidence for the transfer of antibiotic resistance genes from actinobacteria to proteobacteria, highlighting the role of the 'carry-back' mechanism in the dissemination of resistance genes such as cmx and lmrA.
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