Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
nucleotidyl transferase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| Lnu(B) | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 42 | Clindamycin, CLINDAMYCIN +9 |
| South Korea, Brazil, global, Denmark|France|Poland|Italy|Hungary|Germany|Estonia|United States, China, Denmark, Global, Portugal, Spain, Sweden|Italy|Denmark, GA, USA, Estonia|swine, Argentina, Asia|Europe|Americas|China|Taiwan, Europe, Israel, Germany, Minnesota, Chiang Mai province, Northern Thailand|Thailand, South Africa, western Canada|Canada, Ghana, China|UK|Canada|Thailand|Netherlands|USA|Denmark|Spain|other nations, China|Hunan Province, Thailand, Sub-Saharan Africa|Middle East & North Africa|South Asia|Europe |
| 2011, 2013, 2014, 2019, 2020, 2021, 2022, 2023, 2024, 2025 |
| AJ238249.1 |
| CAB41414.1 |
| lnu(B) | ResFinder Database | 1 | CLINDAMYCIN, LINCOMYCIN | Staphylococcus aureus, Enterococcus faecium | - | 2012 | JQ861959, AJ238249 | - |
| lnuB | Card DatabaseReslit | 37 | Clindamycin, Lincomycin +5 | Streptococcus lutetiensis +29 | China, Europe|Asia, Australia, Spain|Canada|Brazil|Thailand, USA|France|Portugal|China|Brazil|Germany|Sweden|Italy|Spain|Denmark|Japan|Korea|Europe|Asia|North America, Europe|EU/EEA|Finland|Switzerland|Spain|Germany|Norway, Hong Kong|China, Europe, United States, Italy, Portugal, Canada|China|Iran|Poland|United States|Turkey|South Korea|Hong Kong|India|Germany|France|Italy|Spain|Japan|Brazil|Australia|Russia|Mexico|Egypt|Saudi Arabia|South Africa|New Zealand|Sweden|Norway|Denmark|Finland|Iceland|Switzerland|Austria|Belgium|Netherlands|Luxembourg|Portugal|Greece|Czech Republic|Hungary|Romania|Bulgaria|Serbia|Croatia|Slovenia|Slovakia|Ukraine|Israel|Jordan|Lebanon|Syria|Iraq|Afghanistan|Pakistan|Bangladesh|Myanmar|Vietnam|Thailand|Malaysia|Indonesia|Philippines|Singapore|Brunei|Cambodia|Laos|Mongolia|North Korea|Taiwan|Macau|Macao|Taipei|Shanghai|Beijing|Guangzhou|Shenzhen|Chengdu|Chongqing|Wuhan|Hangzhou|Nanjing|Xi'an|Tianjin|Harbin|Changchun|Shenyang|Dalian|Qingdao|Ningbo|Wenzhou|Xiamen|Fuzhou|Quanzhou|Zhengzhou|Luoyang|Kaifeng|Zhuhai|Shantou|Zhongshan|Huizhou|Meizhou|Shaoguan|Heyuan|Zhanjiang|Yangjiang|Maoming|Zhaoqing|Jiangmen|Yangzhou|Nantong|Suzhou|Wuxi|Changzhou|Zhenjiang|Taizhou|Lishui|Huzhou|Jiaxing|Shaoxing|Haining|Anqing|Hefei|Huangshan|Wuhu|Ma'anshan|Chizhou|Tongling|Anhui|Hubei|Hunan|Guangxi|Yunnan|Guizhou|Sichuan|Shaanxi|Gansu|Qinghai|Tibet|Inner Mongolia|Xinjiang|Ningxia|Henan|Shanxi|Hebei|Shandong|Jiangsu|Zhejiang|Fujian|Guangdong|Hainan|Jiangxi, Canada|United Kingdom|Alberta, Poland, Denmark, Latvia, Scotland, Spain|Portugal|Germany|UK|Switzerland|Thailand|Italy, Europe|Belgium|France|Germany|Netherlands|United Kingdom, South Korea, Thailand, Mayurbhanj, Odisha, India|India, Europe|UK, Poland|Australia | 2013, 2016, 2017, 2018, 2020, 2021, 2022, 2023, 2024, 2025 | KC688833 | CAB41414.1 |
| lnu B-02 | Reslit | 1 | Lincosamide, Streptogramin b | Escherichia coli | Upper Yangtze River watershed | 2020 | - | - |
Identification of a novel keyhole phenotype in double-disk diffusion assays of clindamycin-resistant erythromycin-sensitive strains of Streptococcus agalactiae.
The study identifies a novel keyhole phenotype in clindamycin-resistant erythromycin-sensitive Streptococcus agalactiae strains, characterized by mutations in the erm(B) gene leading to erythromycin sensitivity despite the presence of the gene, and the presence of the lnu(B) gene associated with clindamycin resistance.
Genetic environment and location of the lnu(A) and lnu(B) genes in methicillin-resistant Staphylococcus aureus and other staphylococci of animal and human origin., A new resistance gene, linB, conferring resistance to lincosamides by nucleotidylation in Enterococcus faecium HM1025.
First case of Streptococcus lutetiensis bacteremia involving a clindamycin-resistant isolate carrying the lnuB gene.
First case of Streptococcus lutetiensis bacteremia involving a clindamycin-resistant isolate carrying the lnuB gene.
The study reports the first case of a clindamycin-resistant Streptococcus lutetiensis isolate carrying the lnuB gene, which confers resistance to clindamycin.
First case of Streptococcus lutetiensis bacteremia involving a clindamycin-resistant isolate carrying the lnuB gene.
First case of Streptococcus lutetiensis bacteremia involving a clindamycin-resistant isolate carrying the lnuB gene.
Characterization of methicillin-resistant coagulase-negative staphylococci in milk from cows with mastitis in Brazil.
The study identified methicillin-resistant coagulase-negative staphylococci (MRCoNS) in milk from cows with mastitis in Brazil, highlighting the presence of various antimicrobial resistance genes including mecA, tet(K), str, ant(4')-I, aac(6')-aph(2"), lnu(B), lsa(E), and a modified erm(C) gene with an 89-bp deletion.
Genomic Analysis Reveals Multi-Drug Resistance Clusters in Group B Streptococcus CC17 Hypervirulent Isolates Causing Neonatal Invasive Disease in Southern Mainland China.
The study identifies multiple antibiotic resistance genes, including tetO, ermB, ant6, aphA, ant9, and lnuB, in Group B Streptococcus CC17 isolates from China, highlighting the emergence of multi-drug resistance in these hypervirulent strains.
Characterization and Comparative Overview of Complete Sequences of the First Plasmids of Pandoraea across Clinical and Non-clinical Strains.
The study characterizes plasmids from various Pandoraea strains, identifying several antibiotic resistance genes including beta-lactamases, tetracycline resistance genes, aminoglycoside resistance genes, fluoroquinolone resistance genes, macrolide resistance genes, chloramphenicol resistance genes, and lincomamide resistance genes.
Transmission of highly virulent community-associated MRSA ST93 and livestock-associated MRSA ST398 between humans and pigs in Australia.
The study identified the presence of CA-MRSA ST93-IV and LA-MRSA ST398-V in Australian pigs, farm workers, and the environment. It also reported the first linezolid-resistant MRSA isolate in Australia. Resistance mechanisms included genes such as blaZ, ermC, fexA, tetK, tetL, vgaA, lnuB, aadD, aadE, and cfr.
Genomic comparisons of Streptococcus suis serotype 9 strains recovered from diseased pigs in Spain and Canada.
The study identified multiple tetracycline, macrolide, lincosamide, and aminoglycoside resistance genes in Streptococcus suis serotype 9 strains, highlighting the widespread presence of antibiotic resistance mechanisms in these isolates.
Antimicrobial Resistance in Streptococcus spp.
The paper discusses the prevalence and mechanisms of antimicrobial resistance in Streptococcus species, particularly focusing on macrolide, lincosamide, and tetracycline resistance. Key genes identified include erm(B), erm(A), lnuB, lnuD, mefA, mefE, msr, tet(B), tet(K), tet(L), tet(M), tet(O), and tet(S).
Combination Therapy Strategies Against Multiple-Resistant Streptococcus Suis.
The study identifies several AMR genes in multidrug-resistant Streptococcus suis isolates, including tetM, lnuB, erm(B), tetO, tetL, and aph3′, which confer resistance to tetracycline, clindamycin, erythromycin, and aminoglycosides.
The draft genomes and investigation of serotype distribution, antimicrobial resistance of group B Streptococcus strains isolated from urine in Suzhou, China.
The study identified several AMR genes in GBS isolates from urine in Suzhou, including tetM, ermB, mefE, lnuB, and others, associated with resistance to tetracycline, erythromycin, clindamycin, and fluoroquinolones.
Antimicrobial Resistance in Staphylococci of Animal Origin
The paper discusses various antimicrobial resistance genes and mutations in staphylococci of animal origin, highlighting their roles in resistance to multiple antibiotics such as macrolides, lincosamides, streptogramins, oxazolidinones, and others. Key genes include erm, msr, mph, ere, lnu, vga, cfr, optrA, dfr, fus, ileS2, blaZ, aadD, ble, fosD, fosB, czrC, and qac genes, which confer resistance to specific antibiotics and are prevalent in different staphylococcal species.
Characterization of a new transferable MDR plasmid carrying the pbp5 gene from a clade B commensal Enterococcus faecium.
Cross-Border Transmission of Salmonella Choleraesuis var. Kunzendorf in European Pigs and Wild Boar: Infection, Genetics, and Evolution.
The study identified multiple antimicrobial resistance genes in Salmonella Choleraesuis isolates, including aadA1, catA1, cmlA1, floR, mph(B), strA, strB, sul1, sul2, sul3, tet(A), tet(B), dfrA1, aph(3')-Ia, lnu(B), and blaTEM-1. These genes conferred resistance to various antibiotics such as streptomycin, chloramphenicol, florfenicol, erythromycin, sulfamethoxazole, tetracycline, trimethoprim, gentamicin, lincomycin, and ampicillin.
New genetic context of lnu(B) composed of two multi-resistance gene clusters in clinical Streptococcus agalactiae ST-19 strains.
The study identifies lnu(B) as the gene responsible for the rare lincosamide resistance (L phenotype) in clinical Streptococcus agalactiae ST-19 strains, highlighting its role in multidrug resistance through a composite transposon structure.
Antimicrobial Resistance and Virulence Gene Profiles of Methicillin-Resistant and -Susceptible Staphylococcus aureus From Food Products in Denmark.
The study identified several antimicrobial resistance genes, including blaZ, tet(K), tet(L), tet(M), and various erm genes, in Staphylococcus aureus isolates from food products in Denmark. Additionally, the tst gene was detected in CC398 and CC45 isolates, indicating the presence of toxic shock syndrome toxin.
Antimicrobial Resistance in Clostridium and Brachyspira spp. and Other Anaerobes.
The paper describes the antimicrobial resistance mechanisms in Clostridium and Brachyspira spp. and other anaerobes, focusing on the genetic basis of resistance to various antibiotics, including tetracyclines, macrolides, lincosamides, chloramphenicol, and others. It highlights the role of specific genes such as tet, erm, and cat in conferring resistance.
Next-Generation Sequencing and MALDI Mass Spectrometry in the Study of Multiresistant Processed Meat Vancomycin-Resistant Enterococci (VRE).
The study identified multiple AMR genes in vancomycin-resistant enterococci (VRE) isolated from processed meat, including vanA, vanC1, erm(B), aac(6')-Ii, aadE, ant(9)-Ia, lsa(E), msr(C), lnu(B), tet(M)+tet(L), dfrG, dfrK, adeC, and efmA, which confer resistance to various antibiotics such as vancomycin, erythromycin, tetracycline, aminoglycosides, and trimethoprim.
Occurrence and distribution of antibiotic resistance genes in various rural environmental media.
The study identified several antibiotic resistance genes (ARGs) in various rural environmental media, including bla OXA10-02, bla PSE, lnu B-02, and qac EΔ1-01, which were found to confer resistance to beta-lactam, lincosamide, streptogramin B, and quaternary ammonium compounds, respectively.
Simultaneous Nasal Carriage by Methicillin-Resistant and Methicillin Susceptible Staphylococcus aureus of Lineage ST398 in a Live Pig Transporter.
The study characterizes two S. aureus ST398 strains, one methicillin-resistant (MRSA) and one methicillin-susceptible (MSSA), isolated from a pig transporter. The MRSA strain harbors the mecA gene, while the MSSA strain lacks it due to a large deletion. Both strains exhibit resistance to several antibiotics including tetracycline, lincosamides, aminoglycosides, and trimethoprim.
The European Union summary report on antimicrobial resistance in zoonotic and indicator bacteria from humans, animals and food in 2015.
The report highlights the presence of various AMR genes and mutations in zoonotic and indicator bacteria, including blaCTX-M-9, blaSHV-12, erm(B), mcr-1, and mcr-2, which confer resistance to beta-lactams, macrolides, and colistin. It emphasizes the importance of monitoring AMR in food-producing animals and humans.
Multidrug-Resistant Streptococcus agalactiae Strains Found in Human and Fish with High Penicillin and Cefotaxime Non-Susceptibilities.
The study identifies multidrug-resistant Streptococcus agalactiae strains with high penicillin and cefotaxime non-susceptibilities, highlighting the emergence of MDR and PEN-NS GBS in both human and aquatic environments.
Comparative genome analysis of Erysipelothrix rhusiopathiae isolated from domestic pigs and wild boars suggests host adaptation and selective pressure from the use of antibiotics.
The study identified tetracycline resistance gene tet(M), and combinations of lsa(E) and lnu(B) conferring resistance to lincosamides, pleuromutilins, and streptogramin A in Erysipelothrix rhusiopathiae isolates from pigs, but not in wild boar isolates.
The European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2017/2018.
The report highlights the prevalence of antimicrobial resistance in zoonotic and indicator bacteria, focusing on Salmonella, Campylobacter, and E. coli. It notes high resistance levels to ampicillin, sulfonamides, and tetracyclines in Salmonella and E. coli isolates, along with rising resistance to fluoroquinolones in certain serovars. Carbapenemase-producing E. coli and Salmonella were rarely detected.
Antimicrobial Resistance Gene Detection and Plasmid Typing Among Multidrug Resistant Enterococci Isolated from Freshwater Environment.
The study identified twelve antimicrobial resistance genes in multidrug-resistant Enterococcus isolates from freshwater, including genes conferring resistance to tetracycline, erythromycin, tylosin, kanamycin, streptomycin, and ciprofloxacin. These genes were detected through PCR and sequencing, highlighting the diversity of resistance mechanisms in environmental Enterococcus.
Early Inoculation of Microbial Suspension in Suckling Piglets Affects the Transmission of Maternal Microbiota and the Associated Antibiotic Resistance Genes.
The study shows that early inoculation of microbial suspensions affects the transmission of maternal microbiota and the associated antibiotic resistance genes (ARGs) in piglets. Specific ARGs such as aadE_2, aphA3, ermB, lnuB, vanTG, tetQ, tnpA, mpmB, lnuC, and tetW were found to be influenced by the inoculation of microbial suspensions S1 and S2.
Evidence for the Dissemination to Humans of Methicillin-Resistant Staphylococcus aureus ST398 through the Pork Production Chain: A Study in a Portuguese Slaughterhouse.
The study identified multiple antimicrobial resistance genes in MRSA ST398 isolates from a Portuguese slaughterhouse, highlighting the dissemination of these resistant strains through the pork production chain and their potential to colonize humans.
Predominance of III/ST19 and Ib/ST10 Lineages With High Multidrug Resistance in Fluoroquinolone-Resistant Group B Streptococci Isolates in Which a New Integrative and Conjugative Element Was Identified.
The study identifies mutations in gyrA and parC genes contributing to fluoroquinolone resistance in Group B Streptococcus (GBS) isolates, along with the presence of resistance genes tetM, ermB, and lnuB. A new integrative and conjugative element (ICE) carrying tetM and gyrA was also identified.
SWINE VIRULENCE ASSESSMENT
This study analyzed the virulence and genomic characteristics of nine United States Streptococcus suis isolates, identifying genomic attributes associated with swine-virulent phenotypes. However, no specific AMR genes or mutations were experimentally validated in this paper.
Molecular Characterization of Enterococcus Isolates From Different Sources in Estonia Reveals Potential Transmission of Resistance Genes Among Different Reservoirs.
The study identified vanB genes in two vancomycin-resistant E. faecalis isolates and characterized various tetracycline, macrolide, lincosamide, and aminoglycoside resistance genes in E. faecalis and E. faecium isolates from different sources in Estonia.
Multidrug Resistance and Molecular Characterization of Streptococcus agalactiae Isolates From Dairy Cattle With Mastitis.
The study identified several AMR genes in S. agalactiae isolates from dairy cattle with mastitis, including tet(O), ermB, lnu(B), and aphA3, which confer resistance to tetracycline, erythromycin, clindamycin, pirlimycin, and kanamycin.
Emergence of Invasive Serotype Ib Sequence Type 10 Group B Streptococcus Disease in Chinese Infants Is Driven by a Tetracycline-Sensitive Clone.
The study identifies the emergence of invasive serotype Ib sequence type 10 Group B Streptococcus (GBS) disease in Chinese infants, highlighting the presence of multiple resistance mechanisms including ermB, mefA, lnuB, tetM, and tetO genes, along with fluoroquinolone resistance mediated by mutations in gyrA and parC.
Molecular Evolution and Adaptation of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA) Sequence Type 9.
The study identifies multiple AMR genes and mutations in ST9 S. aureus, including mecA, blaZ, lnu(B), lsa(E), erm(C), fexA, tet(L), dfrG, vwb, and the MDR ST9 element, highlighting their role in multidrug resistance and host adaptation.
Molecular Characteristics of IS1216 Carrying Multidrug Resistance Gene Cluster in Serotype III/Sequence Type 19 Group B Streptococcus.
The study identified multidrug resistance gene clusters in non-srr1/2 serotype III Group B Streptococcus (GBS) isolates, including lnu(B), lsa(E), aadK, aadE, and aac(3)-IV, which confer resistance to lincosamides, streptomycin, and aminoglycosides.
Whole Genome Analysis of Three Multi-Drug Resistant Listeria innocua and Genomic Insights Into Their Relatedness With Resistant Listeria monocytogenes.
The study identified multiple AMR genes in three multi-drug resistant L. innocua isolates, including tet(M), optrA, fexA, dfrG, lnu(B), lsa(E), ant(6)-Ia, erm(B), aph(3')-IIIa, catA8, lnu(A), msr(D), and mef(A). These genes confer resistance to various antibiotics such as tetracycline, oxazolidinones, fluoroquinolones, trimethoprim, lincomycin, macrolides, aminoglycosides, and chloramphenicol.
Genetic description of VanD phenotype vanA genotype in vancomycin-resistant Enterococcus faecium isolates from a Bone Marrow Transplantation Unit.
The study characterizes the genetic structure of vancomycin-resistant Enterococcus faecium isolates displaying a VanD phenotype with a vanA genotype, highlighting the presence of various resistance genes and genetic variations within the van transposon.
Invasive Multidrug-Resistant emm93.0 Streptococcus pyogenes Strain Harboring a Novel Genomic Island, Israel, 2017-2019.
The study identified multidrug resistance in an emm93.0 Streptococcus pyogenes strain in Israel, including resistance to clindamycin, tetracycline, and trimethoprim/sulfamethoxazole. A novel genomic island containing resistance genes lsa(E), lnu(B), ant(6)-Ia, and aph(3')-IIIa was discovered.
New Sequence Types and Antimicrobial Drug-Resistant Strains of Streptococcus suis in Diseased Pigs, Italy, 2017-2019.
The study identified several AMR genes in Streptococcus suis isolates from diseased pigs in Italy, including ermb, tet(O), aac6-aph2, ant6-ia, aph3-iiia, spw, tet(40), tet(W), tet(O/W/32/O), tet(W/N/N), erm(47), lnuB, lsaE, and optrA, which confer resistance to various antibiotics such as erythromycin, tetracycline, gentamicin, lincomycin, and linezolid.
Emerging Fatal Ib/CC12 Hypervirulent Multiresistant Streptococcus agalactiae in Young Infants With Bloodstream Infection in China.
The study identifies multiple antibiotic resistance genes in Ib/CC12 Streptococcus agalactiae strains, including genes conferring resistance to macrolides, clindamycin, aminoglycosides, tetracycline, and other antibiotics.
Antimicrobial and Biocide Resistance among Feline and Canine Staphylococcus aureus and Staphylococcus pseudintermedius Isolates from Diagnostic Submissions.
The study identified various antimicrobial resistance genes in feline and canine Staphylococcus aureus and Staphylococcus pseudintermedius isolates, including blaZ, mecA, mecC, tet(K), tet(M), erm(A), erm(B), erm(C), erm(T), msr(A), aadE, aacA-aphD, aphA3, aadD, dfrG, lnu(B), and lsa(E). These genes conferred resistance to multiple antibiotics such as penicillins, tetracyclines, macrolides, aminoglycosides, and others.
Antimicrobial Resistance and Clonal Lineages of Staphylococcus aureus from Cattle, Their Handlers, and Their Surroundings: A Cross-Sectional Study from the One Health Perspective.
The study identified various antimicrobial resistance genes in Staphylococcus aureus isolates from cattle, farm workers, and their environment, highlighting the potential for transmission between hosts and the need for monitoring AMR in One Health contexts.
A review of the emergence of antibiotic resistance in bioaerosols and its monitoring methods.
This review highlights the presence of various antibiotic resistance genes (ARGs) in bioaerosols, emphasizing their role in the spread of antibiotic resistance through horizontal gene transfer. Key ARGs identified include those conferring resistance to beta-lactams, tetracyclines, sulfonamides, quinolones, and macrolides.
The impacts of viral infection and subsequent antimicrobials on the microbiome-resistome of growing pigs.
The study identified ermG as a gene that increased in abundance in the feces of treated pigs compared to those that did not receive post-PRRS antimicrobials, indicating its role in macrolide, lincosamide, and streptogramin B resistance.
Exploring the mobilome and resistome of Enterococcus faecium in a One Health context across two continents.
The study identifies various AMR genes in Enterococcus faecium, including vanA, vanB, ermB, ermT, ermA, aad(6), aph(3')-IIIa, aac(6')-Ie-aph(2')-Ia, sat-4, tetM, tet(W/N/W), dfrG, dfrF, lnuB, optrA, and lsaE, which are associated with different habitats and geographic locations.
Antimicrobial Resistance and Virulence Characterization of Listeria monocytogenes Strains Isolated from Food and Food Processing Environments.
The study identified several AMR genes in L. monocytogenes strains, including Lde, aadB, aac(3)-IIa(aacC2), sulI, sulII, lnuA, lnuB, and mefA, which confer resistance to ciprofloxacin, gentamicin, trimethoprim-sulfamethoxazole, and clindamycin.
Genetic diversity and variation in antimicrobial-resistance determinants of non-serotype 2 Streptococcus suis isolates from healthy pigs.
The study identified 18 AMR genes in non-serotype 2 Streptococcus suis isolates from healthy pigs, including genes conferring resistance to aminoglycosides, macrolides, lincosamides, tetracyclines, oxazolidinones, nucleosides, and phenicols.
Comparative virulence and antimicrobial resistance distribution of Streptococcus suis isolates obtained from the United States.
The study identified several antimicrobial resistance (AMR) genes in Streptococcus suis isolates from the United States, including ble, tetO, ermB, lsaE, lnuB, ant(9)-Ia, and ant(6)-Ia, which confer resistance to glycopeptides, tetracyclines, macrolide-lincosamide-streptogramin B, pleuromutilins, and aminoglycosides respectively.
Plasmid-Coded Linezolid Resistance in Methicillin-Resistant Staphylococcus aureus from Food and Livestock in Germany.
Two linezolid-resistant MRSA strains from pigs in Germany were identified, both harboring plasmid-encoded cfr genes. These strains also had additional AMR genes, indicating multidrug resistance.
Farming Practice Influences Antimicrobial Resistance Burden of Non-Aureus Staphylococci in Pig Husbandries.
The study found that organic and alternative pig farming practices are associated with reduced antimicrobial resistance (AMR) in non-aureus staphylococci (NAS) compared to conventional farming. Specific AMR genes such as mecA, blaZ, blaPC1, and others were more prevalent in conventional farms, while organic farms showed lower levels of AMR genes for aminoglycosides, phenicols, and tetracyclines.
Molecular epidemiology, drug resistance, and virulence gene analysis of Streptococcus agalactiae isolates from dairy goats in backyard farms in China.
The study identified multiple AMR genes in S. agalactiae isolates from dairy goats in China, including pbp2b, tetL, tetM, tetK, tetO, ermA, ermB, mefA, aphA3, aad6, lnu(B), gryA, and parC, which confer resistance to various antibiotics such as penicillins, tetracyclines, macrolides, aminoglycosides, lincosamides, and quinolones.
Genomic Diversity of Methicillin-Resistant Staphylococcus aureus CC398 Isolates Collected from Diseased Swine in the German National Resistance Monitoring Program GERM-Vet from 2007 to 2019.
The study identified numerous antimicrobial resistance (AMR) genes in methicillin-resistant Staphylococcus aureus (MRSA) CC398 isolates from diseased swine in Germany, including beta-lactam, tetracycline, macrolide, lincosamide, streptogramin B, phenicol, aminoglycoside, and fluoroquinolone resistance genes. These genes were often located on small transposons or plasmids, contributing to the multidrug resistance profile of the isolates.
The effects of antibiotic use on the dynamics of the microbiome and resistome in pigs.
The study identified several antibiotic resistance genes (ARGs) in porcine fecal microbiota, including aacA-aphD, ermT, lnuB, strB, sul2, tetA, tetM, and blaTEM, which showed increased abundance in antibiotic-treated pigs compared to untreated pigs.
Antimicrobial resistance and whole genome sequencing of novel sequence types of Enterococcus faecalis, Enterococcus faecium, and Enterococcus durans isolated from livestock.
The study identifies several antimicrobial resistance genes in Enterococcus species isolated from livestock in South Africa, highlighting the presence of multidrug-resistant strains and emphasizing the need for genomic surveillance to monitor the spread of antimicrobial resistance in food chain animals.
Antimicrobial resistance in Enterococcus isolated from western Canadian cow-calf herds.
The study identified several AMR genes in Enterococcus isolates from cow-calf herds, including resistance to lincomycin, quinupristin/dalfopristin, daptomycin, ciprofloxacin, and tetracycline.
Enterococcus species: insights into antimicrobial resistance and whole-genome features of isolates recovered from livestock and raw meat in Ghana.
The study identified various antimicrobial resistance genes in Enterococcus spp. isolated from livestock and raw meat in Ghana, including genes conferring resistance to erythromycin, tetracycline, chloramphenicol, and other antibiotics. Notable genes include aac(6')-Ii, aph(3')-III, ant(6)-Ia, erm(B), erm(T), msr(C), lsa(A), lsa(E), lnu(B), tet(L), tet(M), tet(S), dfrG, cat, pbp5, and ClpL.
Streptococcus suis Research Update: Serotype Prevalence and Antimicrobial Resistance Distribution in Swine Isolates Recovered in Spain from 2020 to 2022.
The study identified the prevalence of antimicrobial resistance genes in Streptococcus suis isolates from Spain, including tet(O), erm(B), lnu(B), lsa(E), tet(M), and mef(A/E). High resistance levels were observed for clindamycin, chlortetracycline, and sulfadimethoxine.
Macrolide and lincosamide resistance of Streptococcus agalactiae in pregnant women in Poland.
The study identifies the ermB, mefA, ermA, lnuB, lsaE, and tetM genes as key contributors to macrolide and lincosamide resistance in Streptococcus agalactiae isolates from pregnant women in Poland.
Streptococcus suis serotype 4: a population with the potential pathogenicity in humans and pigs.
The study identified multiple antibiotic resistance genes in Streptococcus suis serotype 4, including genes conferring resistance to tetracyclines, macrolides, lincosamides, aminoglycosides, oxazolidinones, and chloramphenicol. Prophages were identified as the primary vehicle for the dissemination of these resistance genes.
Integrative and Conjugative Elements and Prophage DNA as Carriers of Resistance Genes in Erysipelothrix rhusiopathiae Strains from Domestic Geese in Poland.
The study identifies the presence of resistance genes erm47 and ermB in Erysipelothrix rhusiopathiae strains from domestic geese in Poland, along with other resistance genes such as tetM, lnuB, lsaE, ant(6)-Ia, and spw. It also highlights the role of integrative and conjugative elements (ICEs) and prophage DNA in the spread of these resistance genes.
Evaluation of Antimicrobial Resistancein Clinical Isolates of Enterococcus spp. Obtained from Hospital Patients in Latvia.
The study identifies several AMR genes and mutations in Enterococcus isolates, including vanB for vancomycin resistance, lsaA, lsaE, lnuB for lincosamide resistance, tetM and tetL for tetracycline resistance, aac6'-Ii, aac6'-aph2'', aph3'-III, and ant6-Ia for aminoglycoside resistance, msrC, ermB, and ermT for macrolide resistance, and mutations in gyrA, parC, pbp5, and 23S rRNA for fluoroquinolone, penicillin, and linezolid resistance.
Emergence of novel methicillin resistant Staphylococcus pseudintermedius lineages revealed by whole genome sequencing of isolates from companion animals and humans in Scotland.
The study identified novel methicillin-resistant Staphylococcus pseudintermedius (MRSP) lineages, including ST726 and ST551, and characterized antimicrobial resistance genes such as mecA, blaZ, tetK, and mupA. It also noted a high prevalence of multidrug resistance (MDR) among MRSP isolates.
Antimicrobial Resistance in Coagulase-Negative Staphylococci: Resistome, Mobiloome, and Relatedness
The study identifies multiple AMR genes and mutations in CoNS isolates from various hosts, highlighting the spread of multidrug resistance and the role of mobile genetic elements in the dissemination of resistance traits.
Molecular characterization of Streptococcus suis isolates recovered from diseased pigs in Europe.
The study identified high frequencies of tetracycline and macrolide resistance genes, specifically tetO and ermB, in European Streptococcus suis isolates.
Prevalence of pathogens and antimicrobial resistance of isolated Staphylococcus spp. in bovine mastitis milk in South Korea, 2018-2022.
The study identified several antimicrobial resistance genes in Staphylococcus spp. isolated from bovine mastitis milk, including mecA, blaZ, tetK, ermC, lnuA, and lnuB. These genes were associated with resistance to penicillins, tetracyclines, erythromycin, and lincomycin.
Antibiotic Resistance and Serotypes Distribution in Streptococcus agalactiae Bulgarian Clinical Isolates During the Years of 2021-2024.
The study identified several AMR genes associated with macrolide, lincosamide, and tetracycline resistance in Streptococcus agalactiae isolates from Bulgaria. These include ermB, ermA/TR, ermC, mefA, mefE, msrD, lnuB, lsaC, lsaE, tetM, and tetO. High resistance rates to macrolides (60.3%) and tetracyclines (89.1%) were observed.
The healthy human gut can take it all: vancomycin-variable, linezolid-resistant strains and specific bacteriocin-species interplay in Enterococcus spp.
The study identifies linezolid resistance genes optrA and poxtA in Enterococcus faecium and Enterococcus thailandicus isolates, along with a vancomycin-variable E. faecium strain. It also reveals the increasing prevalence of E. lactis in the healthy human gut and the complex interplay of bacteriocin gene profiles among Enterococcus species.
Characteristic profiles of molecular types, antibiotic resistance, antibiotic resistance genes, and virulence genes of Staphylococcus aureus isolates from caprine mastitis in China.
The study identified several AMR genes in S. aureus isolates from caprine mastitis in China, including blaZ, mecA, tetK, tetM, ermB, lnu(B), aacA-aphD, and gyrA, which confer resistance to various antibiotics such as penicillin, oxacillin, tetracycline, erythromycin, lincomycin, gentamicin, amikacin, and fluoroquinolones.
Predomination of hypervirulent ST283 and genetic diversity of levofloxacin resistance in multidrug-resistant, hypervirulent Streptococcus agalactiae in Thailand.
The study identified multiple AMR genes and mutations associated with tetracycline, erythromycin, clindamycin, and levofloxacin resistance in multidrug-resistant, hypervirulent Streptococcus agalactiae isolates in Thailand, highlighting the predominance of hypervirulent ST283 and the emergence of MDR-GBS.
Prevalence and antimicrobial resistance of methicillin-resistant and methicillin-susceptible Staphylococcus in small- to medium-scale and large-scale dairy farms in Thailand.
The study identified several AMR genes and mutations in Staphylococcus isolates from small- to medium-scale and large-scale dairy farms in Thailand, highlighting differences in resistance profiles between farm types.
Unveiling community structure, antimicrobial resistance, and virulence factor of a wastewater sample of dairy farm located in mayurbhanj, odisha, india.
The study identified several antimicrobial resistance (AMR) genes in a dairy wastewater sample, including beta-lactamases, aminoglycoside acetyltransferases, tetracycline resistance proteins, quinolone resistance proteins, and macrolide ribosome methyltransferases. These genes were found in various bacterial species such as Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, and Pseudomonas aeruginosa.
Phenotypic and genomic analysis of the emerging poultry pathogen Enterococcus cecorum in UK isolates.
The study identifies multiple AMR genes and mutations in UK E. cecorum isolates, including tet(L), tet(M), ant(6)-la, ermB, NarA/NarB, and lnuC, as well as mutations in pbp2x and gyrA that confer resistance to various antibiotics.
Antibiotic resistance in mastitis-causing bacteria: Exploring antibiotic-resistance genes, underlying mechanisms, and their implications for dairy animal and public health.
The study identifies several AMR genes and mutations in Staphylococcus aureus and coagulase-negative staphylococci associated with mastitis, including blaZ, mecA, tetK, tetM, aphA3, aacA-aphD, aadD, ermA, msrA, mphC, lnuB, and vanA, which confer resistance to various antibiotics such as β-lactams, tetracyclines, aminoglycosides, macrolides, and glycopeptides.
Geographics and bacterial networks differently shape the acquired and latent global sewage resistomes.
The study identifies several AMR genes, including aph(6)-id_2, mef(c), mef(b), mph(e), mph(g), msr(d), lnu(b), lnu(d), aadA, ant(6)-Ia, blaCTX-M, blaTEM, blaSHV, blaOXA, qnrS1, mcr-1, and vanA, which are associated with resistance to various antibiotics such as aminoglycosides, macrolides, lincosamides, beta-lactams, fluoroquinolones, polymyxins, and glycopeptides.
Temporal dynamics of the resistome in gilts raised in an organic operation in which semen used for artificial insemination is the primary source of antimicrobial exposure.
The study identified several tetracycline, aminoglycoside, and MLS resistance genes in the fecal microbiome of gilts, with no significant increases in ARG abundance following exposure to semen extenders containing antibiotics.
Prophage φEr670 and Genomic Island GI_Er147 as Carriers of Resistance Genes in Erysipelothrix rhusiopathiae Strains.
The study identifies the prophage φEr670 carrying lnuB and lsaE genes, and the genomic island GI_Er147 carrying ant(6)-Ia, spw, lnu(J), and vat family genes in E. rhusiopathiae strains. These genes confer resistance to lincomycin, tetracycline, streptomycin, and spectinomycin.
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