Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
lincosamide nucleotidyltransferase Lnu(G)
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| lnu(G) | ResFinder Database | 1 | LINCOMYCIN | Enterococcus faecalis | - | 2017 | KX470419 | - |
| Lnu(G) | Card DatabaseReference Gene Catalog |
| 16 |
| LINCOSAMIDE, Lincomycin +3 |
| Enterococcus faecium EnGen0001 +14 |
| France|Portugal, Ontario, Canada|North America, China, Global, Vermont, Portugal, Europe, China|North America|Asia|Europe|Africa|Other, Shenzhen, China |
| 2017, 2018, 2021, 2022, 2023, 2024, 2025 |
| AHWZ01000002.1 |
| ELA98712.1 |
| lnuG | Card DatabaseReslit | 3 | Lincomycin | Escherichia coli +2 | Peruvian Amazon, North America|East Asia|Europe | 2023, 2025 | PRJNA992559 | APU52409.1 |
Novel lnu(G) gene conferring resistance to lincomycin by nucleotidylation, located on Tn6260 from Enterococcus faecalis E531.
Novel lnu(G) gene conferring resistance to lincomycin by nucleotidylation, located on Tn6260 from Enterococcus faecalis E531.
Novel lnu(G) gene conferring resistance to lincomycin by nucleotidylation, located on Tn6260 from Enterococcus faecalis E531.
Whole-Genome Sequence Analysis of Multidrug-Resistant Campylobacter Isolates: a Focus on Aminoglycoside Resistance Determinants.
The study identified two new aminoglycoside phosphotransferase genes (aph(2")-Ii1 and aph(2")-Ii2) associated with gentamicin resistance, a lincosamide nucleotidyltransferase gene (lnu(G)) linked to lincomycin resistance, and new resistance enzymes (apmA and spw) potentially conferring resistance to spectinomycin and gentamicin. Additionally, ant(6)-Ig and ant(6)-If were found to be associated with streptomycin resistance, while ant(9)-Ic was linked to spectinomycin resistance.
On-Farm Anaerobic Digestion of Dairy Manure Reduces the Abundance of Antibiotic Resistance-Associated Gene Targets and the Potential for Plasmid Transfer.
The study found that anaerobic digestion of dairy manure significantly reduced the abundance of antibiotic resistance genes, including various ESBL genes such as bla CTX-M-1, bla CTX-M-14, bla CTX-M-15, bla CTX-M-27, bla CTX-M-55, and bla PER-1, as well as other resistance genes like aac(6')-Ib-cr, aph(3')-Ib, aph(6)-Id, bla OXA-1, catB4, dfrA1, floR, lnu(G), sul2, aadA2, mph(E), msr(E), tet(C), tet(E), and tet(X).
Genomic Characterization of a Proteus sp. Strain of Animal Origin Co-Carrying bla(NDM-1) and lnu(G).
The study characterizes a carbapenem-resistant Proteus sp. strain, NMG38-2, which co-carries the bla(NDM-1) and lnu(G) genes on a pPvSC3-like plasmid. The bla(NDM-1) gene is associated with carbapenem resistance, while lnu(G) confers resistance to lincosamides.
Genetic Characterization of Four Groups of Chromosome-Borne Accessory Genetic Elements Carrying Drug Resistance Genes in Providencia.
This study characterizes four groups of chromosome-borne accessory genetic elements (AGEs) in Providencia, highlighting the diversity and complexity of multidrug resistance (MDR) regions within these elements. It identifies numerous drug resistance genes, including beta-lactamases, aminoglycoside modifying enzymes, tetracycline resistance genes, and others, contributing to the understanding of AMR mechanisms in Providencia.
Genomic characteristics of clinical multidrug-resistant Proteus isolates from a tertiary care hospital in southwest China.
The study identifies multiple AMR genes in clinical multidrug-resistant Proteus isolates, including bla CTX-M-65, bla OXA-1, bla KPC-2, bla NDM-1, and others, highlighting the genetic diversity of mobile genetic elements carrying resistance genes.
Longitudinal Analysis of Antimicrobial Resistance among Enterococcus Species Isolated from Australian Beef Cattle Faeces at Feedlot Entry and Exit.
Progress in the Prevalence, Classification and Drug Resistance Mechanisms of Methicillin-Resistant Staphylococcus aureus.
The paper reviews the prevalence, classification, and drug resistance mechanisms of methicillin-resistant Staphylococcus aureus (MRSA), focusing on the roles of mecA, mecC, and vanA genes in conferring resistance to beta-lactam and glycopeptide antibiotics.
Genomic insights into ESBL-producing Escherichia coli isolated from non-human primates in the Peruvian Amazon.
The study identified three bla CTX-M variants (bla CTX-M-15, bla CTX-M-55, and bla CTX-M-65) and a broad resistome in ESBL-producing E. coli strains isolated from non-human primates in the Peruvian Amazon.
Hybrid Illumina-Nanopore assembly improves identification of multilocus sequence types and antimicrobial resistance genes of Staphylococcus aureus isolated from Vermont dairy farms: comparison to Illumina-only and R9.4.1 nanopore-only assemblies.
The study identified various antimicrobial resistance genes in Staphylococcus aureus isolates from Vermont dairy farms, including beta-lactam resistance genes (blaZ, blaI, blaR), tetracycline resistance genes (tet(K), tet(38)), erythromycin resistance genes (erm(T), erm(A)), lincomycin resistance gene (lnu(G)), aminoglycoside resistance genes (aaC3, ant(9)-la), multidrug resistance efflux pumps (lmrS, mepA, mepR, mepB, norA, norB, arlS, arlR, mgrA), and fosfomycin resistance gene (fosB).
The healthy human gut can take it all: vancomycin-variable, linezolid-resistant strains and specific bacteriocin-species interplay in Enterococcus spp.
The study identifies linezolid resistance genes optrA and poxtA in Enterococcus faecium and Enterococcus thailandicus isolates, along with a vancomycin-variable E. faecium strain. It also reveals the increasing prevalence of E. lactis in the healthy human gut and the complex interplay of bacteriocin gene profiles among Enterococcus species.
Genomic epidemiology and antimicrobial resistance of Morganella clinical isolates between 2016 and 2023.
The study identified several AMR genes in Morganella clinical isolates, including tet(B), sul1, catA2, sul2, floR, aadA1, and others, contributing to resistance against various antibiotics.
Population and pan-genomic analyses of Staphylococcus pseudintermedius identify geographic distinctions in accessory gene content and novel loci associated with AMR.
The study identifies novel chromosomal loci associated with antimicrobial resistance in Staphylococcus pseudintermedius, including the trimethoprim resistance gene dfRS1, the quinolone resistance determinant grlA_D84H, the lincosamide resistance gene lnuG, and the extended-spectrum beta-lactamase gene blaTEM-116.
Pan-genome analysis of the Enterobacter hormaechei complex highlights its genomic flexibility and pertinence as a multidrug resistant pathogen.
The study identifies a wide range of antibiotic resistance genes in the Enterobacter hormaechei complex, highlighting its multidrug-resistant nature and the role of mobile genetic elements in the dissemination of resistance.
Genomic and clinical characterization of linezolid resistance in Enterococcus species from cancer patients in China.
The study identified the optrA gene as the primary mechanism of linezolid resistance in Enterococcus species from cancer patients in China, along with other resistance genes such as tet(M), erm(A), and erm(B).
Global phylogeography and genomic characterization of bla(NDM-1)-positive clinical Proteus mirabilis isolates from China.
The study identifies blaNDM-1 as a key determinant of carbapenem resistance in Proteus mirabilis isolates from China, along with other resistance genes such as blaCTX-M-14, blaCTX-M-65, and blaTEM-1. It also characterizes the genomic context of blaNDM-1, including its integration into SGI1 and plasmid-borne elements.
Community gut colonization by tet(X4)-positive multidrug-resistant Escherichia coli in healthy individuals from urban residents in Shenzhen, China.
The study identifies tet(X4)-positive multidrug-resistant E. coli in healthy individuals from urban areas in Shenzhen, China, highlighting the presence of tigecycline resistance and other resistance genes in the community gut microbiota.
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