Browse AMR Genes

Explore antimicrobial resistance genes from the literature

lpxL

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to lpxL

Browse AMR rules for lpxL

Overview

Drug Classes: Benzalkonium chloride
Organisms: Escherichia coli
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
A96E	-	-	Escherichia coli	Benzalkonium chloride	Reslit	Candidate

Papers1

1

Persistence against benzalkonium chloride promotes rapid evolution of tolerance during periodic disinfection.

PMID 34815390 · 2021

Mutation in lpxL is associated with reduced cell surface charge and increased tolerance to benzalkonium chloride.

Mutation Information

Protein Change: A96E
Organisms: Escherichia coli
Confers Resistance To: Benzalkonium chloride
Source Database: Reslit