Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
ABC-F type ribosomal protection protein Lsa(B)
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| Lsa(B) | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 7 | STREPTOGRAMIN, VIRGINIAMYCIN M +13 |
| India, global, Germany |
| 2004, 2014, 2022, 2023 |
| AJ579365.1 |
| CAE18141.1 |
| lsa(B) | Card DatabaseResFinder Database | 2 | CLINDAMYCIN, LINCOMYCIN +3 | Mammaliicoccus sciuri | - | 2004 | AJ579365 | CAE18141.1 |
| lsaB | Reslit | 6 | Erythromycin, Tylosin +3 | Bacillus cereus s.l. +7 | Germany, Japan, North America|Europe|International Space Station, China, Canada, La Rioja, Spain | 2019, 2021, 2022, 2024 | LC586958|LC597664|LC596398 | - |
Nucleotide sequence and organization of the multiresistance plasmid pSCFS1 from Staphylococcus sciuri.
Nucleotide sequence and organization of the multiresistance plasmid pSCFS1 from Staphylococcus sciuri.
Nucleotide sequence and organization of the multiresistance plasmid pSCFS1 from Staphylococcus sciuri.
Nucleotide sequence and organization of the multiresistance plasmid pSCFS1 from Staphylococcus sciuri.
A cfr-positive clinical staphylococcal isolate from India with multiple mechanisms of linezolid-resistance.
The study reports a linezolid-resistant Staphylococcus haemolyticus isolate from India carrying the cfr gene, a G2576T mutation in the 23S rRNA gene, and a Met156Thr mutation in the L3 ribosomal protein, indicating multiple mechanisms of linezolid resistance.
Antimicrobial Resistance in Staphylococci of Animal Origin
The paper discusses various antimicrobial resistance genes and mutations in staphylococci of animal origin, highlighting their roles in resistance to multiple antibiotics such as macrolides, lincosamides, streptogramins, oxazolidinones, and others. Key genes include erm, msr, mph, ere, lnu, vga, cfr, optrA, dfr, fus, ileS2, blaZ, aadD, ble, fosD, fosB, czrC, and qac genes, which confer resistance to specific antibiotics and are prevalent in different staphylococcal species.
Antibiotics resistance and toxin profiles of Bacillus cereus-group isolates from fresh vegetables from German retail markets.
The study identified several AMR genes in Bacillus cereus-group isolates from fresh vegetables, including fosB, ykkC, lsaB, and tet(45). These genes were found to confer resistance to various antibiotics such as fosfomycin, tetracycline, and erythromycin.
Antimicrobial Resistance Genes in Bacteria Isolated From Japanese Honey, and Their Potential for Conferring Macrolide and Lincosamide Resistance in the American Foulbrood Pathogen Paenibacillus larvae.
The study identified the ermC gene on the plasmid pJ18TS1mac and the lsaB and oleC genes on an integrative conjugative element (ICE) in honey-derived bacteria, which conferred resistance to tylosin and lincomycin in Paenibacillus larvae. Additionally, the ermL and ermB genes on plasmid pJ45TS6 were found to contribute to macrolide resistance.
Extensive Horizontal Gene Transfer within and between Species of Coagulase-Negative Staphylococcus.
The study identifies various antimicrobial resistance genes in CoNS species, including mecA, norA, vatB, vgaB, lsaB, erm(43), ermT, fusD, fusF, and salA, which confer resistance to beta-lactams, fluoroquinolones, lincosamides, macrolides, streptogramins, fusidic acid, and other antimicrobial agents. These genes are associated with horizontal gene transfer and recombination, highlighting the dynamic nature of CoNS evolution.
Extensive metagenomic analysis of the porcine gut resistome to identify indicators reflecting antimicrobial resistance.
The study identified 1295 open reading frames recognized as antimicrobial resistance protein-coding genes in porcine gut microbiomes, highlighting tetracycline, aminoglycoside, and MLS resistance as predominant. Key ARGs like tet(W/N/W), APH(3')-IIIa, and ErmB were found to be highly prevalent and associated with resistance to specific antibiotics.
Evaluating the potential of third generation metagenomic sequencing for the detection of BRD pathogens and genetic determinants of antimicrobial resistance in chronically ill feedlot cattle.
The study identified various antimicrobial resistance genes (ARGs) in metagenomic sequencing data from chronically ill feedlot cattle, including genes conferring resistance to beta-lactams, aminoglycosides, macrolides, phenicols, tetracyclines, and trimethoprim. Notably, tetH was the most frequently detected resistance gene, and several ARGs were found to be associated with integrative and conjugative elements (ICEs).
Genomic characterization of Bacillus cereus sensu stricto 3A ES isolated from eye shadow cosmetic products.
The study identified several antimicrobial resistance (AMR) genes in B. cereus s.s. 3A-ES, including VanB-type, VanRB, CAT15/16, BcrA, BcrB, Lsa(B), and recA, which contribute to resistance against various antibiotics and preservatives in cosmetic products.
Plasmid-Coded Linezolid Resistance in Methicillin-Resistant Staphylococcus aureus from Food and Livestock in Germany.
Two linezolid-resistant MRSA strains from pigs in Germany were identified, both harboring plasmid-encoded cfr genes. These strains also had additional AMR genes, indicating multidrug resistance.
Genetic Diversification and Resistome of Coagulase-Negative Staphylococci from Nostrils of Healthy Dogs and Dog-Owners in La Rioja, Spain.
The study identified various AMR genes including blaZ, mecA, erm(A), erm(C), erm(T), mph(C), msr(A), vga(A), lsaB, ant4′, aac6′-aph2″, tet(K), tet(M), dfrA, dfrG, catPC221, and mupA in CoNS isolates from healthy dogs and dog-owners. Additionally, a linezolid-resistant S. epidermidis isolate was found to have multiple amino acid substitutions in 50S ribosomal proteins L3 and L4.
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