Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
ABC-F type ribosomal protection protein Lsa(C)
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| Lsa(C) | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 9 | STREPTOGRAMIN, VIRGINIAMYCIN M +11 |
| New Zealand, North America, Saudi Arabia |
| 2011, 2017, 2018, 2020, 2022, 2024 |
| HM990671.1 |
| AEA37904.1 |
| lsa(C) | Card DatabaseResFinder Database | 2 | CLINDAMYCIN, LINCOMYCIN +4 | Streptococcus agalactiae | - | 2011 | HM990671 | AEA37904.1 |
| lsaC | Reslit | 6 | Quinupristin/dalfopristin, Clindamycin +4 | Streptococcus pyogenes +4 | United States, China, Sweden, Europe, Thailand | 2017, 2022, 2023, 2024, 2025 | NCBI:CP000259|NCBI:SRR1574573|NCBI:SRR1574608|NCBI123456|NCBI678901 | - |
Cross-resistance to lincosamides, streptogramins A, and pleuromutilins due to the lsa(C) gene in Streptococcus agalactiae UCN70.
Cross-resistance to lincosamides, streptogramins A, and pleuromutilins due to the lsa(C) gene in Streptococcus agalactiae UCN70.
Cross-resistance to lincosamides, streptogramins A, and pleuromutilins due to the lsa(C) gene in Streptococcus agalactiae UCN70.
Cross-resistance to lincosamides, streptogramins A, and pleuromutilins due to the lsa(C) gene in Streptococcus agalactiae UCN70.
The study identifies the lsa(C) gene as a novel determinant of cross-resistance to lincosamides, streptogramins A, and pleuromutilins in Streptococcus agalactiae UCN70.
Cross-resistance to lincosamides, streptogramins A, and pleuromutilins due to the lsa(C) gene in Streptococcus agalactiae UCN70.
Population and Whole Genome Sequence Based Characterization of Invasive Group A Streptococci Recovered in the United States during 2015.
The study identified several AMR genes and mutations in invasive group A streptococci, including ermT, ermB, ermTR, tetM, lsaC, mef, msrD, and mutations in ParC and GyrA that confer resistance to macrolides, tetracycline, and fluoroquinolones.
The Obscure World of Integrative and Mobilizable Elements, Highly Widespread Elements that Pirate Bacterial Conjugative Systems.
The paper discusses the role of integrative and mobilizable elements (IMEs) in bacterial evolution, focusing on their ability to hijack conjugative systems for their transfer and their potential to carry antibiotic resistance genes.
Critical steps in clinical shotgun metagenomics for the concomitant detection and typing of microbial pathogens.
The study characterizes various AMR genes involved in resistance to multiple antibiotics, including beta-lactams, aminoglycosides, macrolides, tetracyclines, and others, in different bacterial species such as Staphylococcus aureus, Enterococcus faecium, and Serratia marcescens.
Mobilization of IMEs Integrated in the oriT of ICEs Involves Their Own Relaxase Belonging to the Rep-Trans Family of Proteins.
The study identifies lsa(C) as a gene conferring resistance to lincosamides, streptogramin A, and pleuromutilins in various Streptococcus species.
Population Genomics Reveals Distinct Temporal Association with the Emergence of ST1 Serotype V Group B Streptococcus and Macrolide Resistance in North America.
The study identifies macrolide resistance genes erm(A), erm(B), and lsa(C) in ST1 serotype V Group B Streptococcus, highlighting their association with increased macrolide resistance in adult invasive disease.
Antibiotic resistance and pathogenicity assessment of various Gardnerella sp. strains in local China.
The study identified antibiotic resistance genes ermX, lsaC, tetL, and tetM in Gardnerella strains, with seven strains showing strong resistance to metronidazole.
Antimicrobial Resistance in Vaginal Bacteria in Inseminated Mares.
The study identified several AMR genes in E. coli, S. equisimilis, and S. simulans, including sul1, sul2, dfrA1, dfrA14, tet(A), mdf(A), blaEC-5, blaTEM-1, blaTEM-1B, blaEC, catB3, aadA5, aph(6)-ld, lsaC, and blaZ, which conferred resistance to various antibiotics.
Genomic insights into the diversity, virulence, and antimicrobial resistance of group B Streptococcus clinical isolates from Saudi Arabia.
The study identified several AMR genes including erm(B), erm(A), lsa(C), mef(A), tet(M), tet(O), aac(6')-aph(2''), ant(6)-Ia, aph(3')-III, and aadE in GBS isolates from Saudi Arabia, highlighting the prevalence of resistance to macrolides, lincosamides, tetracycline, and aminoglycosides.
Antibiotic Resistance and Serotypes Distribution in Streptococcus agalactiae Bulgarian Clinical Isolates During the Years of 2021-2024.
The study identified several AMR genes associated with macrolide, lincosamide, and tetracycline resistance in Streptococcus agalactiae isolates from Bulgaria. These include ermB, ermA/TR, ermC, mefA, mefE, msrD, lnuB, lsaC, lsaE, tetM, and tetO. High resistance rates to macrolides (60.3%) and tetracyclines (89.1%) were observed.
Predomination of hypervirulent ST283 and genetic diversity of levofloxacin resistance in multidrug-resistant, hypervirulent Streptococcus agalactiae in Thailand.
The study identified multiple AMR genes and mutations associated with tetracycline, erythromycin, clindamycin, and levofloxacin resistance in multidrug-resistant, hypervirulent Streptococcus agalactiae isolates in Thailand, highlighting the predominance of hypervirulent ST283 and the emergence of MDR-GBS.
Two Independent Acquisitions of Multidrug Resistance Gene lsaC in Streptococcus pneumoniae Serotype 20 Multilocus Sequence Type 1257.
The study identifies two independent acquisitions of the multidrug resistance gene lsaC in Streptococcus pneumoniae serotype 20 multilocus sequence type 1257, which confers resistance to clindamycin and pleuromutilins.
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