Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| G357A | - | modest effect on the MP domain of MacA | Escherichia coli | Erythromycin|Oleandomycin | Reslit | Candidate |
| G353A | - | disrupts the proper assembly of the MacA-MacB complex | Escherichia coli | Erythromycin|Oleandomycin | Reslit | Candidate |
| - | reduces resistance to macrolides in vivo | Escherichia coli |
Reslit |
| Candidate |
The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by MacB transporter.
The G353A mutation in MacA reduces resistance to macrolides in vivo.
© 2026 ResLit. Data sourced from PubMed literature analysis.
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