map

type I methionyl aminopeptidase (MetAP1)

Validation StatusCandidate

Overview

Mechanism: serine-to-valine substitution (S76V)
Validation Method: genomic sequencing
Drug Classes: Streptomycin
Organisms: Erwinia amylovora
Geographic Location: South Korea
Papers: 1
Databases: Reslit

Papers1

Unveiling Antibiotic Resistance: Genome Sequencing of Streptomycin-Resistant Erwinia amylovora Isolate.

PMID 39770697 · 2024

The study identifies two mutations in the rpsL and map genes of a streptomycin-resistant Erwinia amylovora isolate, EaSmR, which confer high-level streptomycin resistance.

Gene Information

Gene Name: map
Allele: map
Encodes: type I methionyl aminopeptidase (MetAP1)
Source Database: Reslit
Mechanism: serine-to-valine substitution (S76V)
Confers Resistance To: Streptomycin
Organisms Tested In: • Erwinia amylovora
Geographic Location: South Korea
Validation Method: genomic sequencing
Sequence Accession: GCA_013375015.1|GCF_002952315.1|CP171267|CP171268

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