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Explore antimicrobial resistance genes from the literature
phosphoethanolamine--lipid A transferase MCR-6.1
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| mcr-6.1 | ResFinder Database | 1 | COLISTIN | Moraxella sp. MSG47-C17 | - | 2017 | MF176240 | - |
| MCR-6.1 | Card DatabaseReference Gene Catalog |
| 3 |
| COLISTIN |
| Moraxella sp. MSG47-C17 |
| - |
| 2018 |
| MF176240.1 |
| ASK49942.1 |
mcr-1 and mcr-2 variant genes identified in Moraxella species isolated from pigs in Great Britain from 2014 to 2015.
mcr-1 and mcr-2 (mcr-6.1) variant genes identified in Moraxella species isolated from pigs in Great Britain from 2014 to 2015.
mcr-1 and mcr-2 (mcr-6.1) variant genes identified in Moraxella species isolated from pigs in Great Britain from 2014 to 2015.
mcr-1 and mcr-2 (mcr-6.1) variant genes identified in Moraxella species isolated from pigs in Great Britain from 2014 to 2015.
Proposal for assignment of allele numbers for mobile colistin resistance (mcr) genes.
The paper proposes a standardized nomenclature for mobile colistin resistance (mcr) genes, focusing on the assignment of allele numbers to ensure clarity and consistency in identifying and characterizing these genes across different bacterial species and geographic locations.
Colistin and its role in the Era of antibiotic resistance: an extended review (2000-2019)
The paper reviews the mechanisms of colistin resistance in multidrug-resistant Gram-negative bacteria, highlighting chromosomal mutations in genes such as pmrA, pmrB, phoP, phoQ, and mgrB that alter LPS modifications and contribute to resistance.
Current Update on Intrinsic and Acquired Colistin Resistance Mechanisms in Bacteria.
The paper reviews intrinsic and acquired colistin resistance mechanisms in bacteria, highlighting the role of genes such as pmrA, pmrB, phoP, phoQ, mgrB, arnBCADTEF, and mcr genes in conferring resistance. It discusses the importance of these genes in the context of colistin resistance and their implications for clinical treatment.
Global epidemiology, genetic environment, risk factors and therapeutic prospects of mcr genes: A current and emerging update.
The paper reviews the global epidemiology, genetic environment, risk factors, and therapeutic prospects of mcr genes, highlighting their dissemination in Enterobacteriaceae species and the role of mobile genetic elements in their spread. It identifies multiple mcr genes, including mcr-1 to mcr-10, and discusses their mechanisms of colistin resistance.
Understanding Recent Developments in Colistin Resistance: Mechanisms, Clinical Implications, and Future Perspectives.
The paper discusses the emergence and spread of plasmid-mediated MCR genes (MCR-1 to MCR-10) that confer colistin resistance in Gram-negative bacteria, emphasizing their role in reducing the efficacy of colistin as a last-resort antibiotic.
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