Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
efflux pump component
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| V610F | - | - | Escherichia coli | Fluoroquinolones|Macrolide|OxazolidinoneLinezolid|Tetracycline | Reslit | Candidate |
Metagenomic read cloud sequencing reveals antibiotic resistance gene dynamics in the gut microbiome of a hematopoietic cell transplant patient
The study identified 46 antibiotic resistance genes in the pre-transplant E. coli strain, including genes conferring resistance to beta-lactams, aminoglycosides, polymyxins, bacitracin, and multiple drugs through efflux pumps.
Acceleration of emergence of E. coli antibiotic resistance in a simulated sublethal concentration of copper and tetracycline co-contaminated environment.
The study identifies mdtF and vanRI as genes involved in the development of resistance to polymyxin B and chloramphenicol in E. coli K12 under sublethal copper and tetracycline co-contaminated conditions.
Combined exposure to non-antibiotic pharmaceutics and antibiotics in the gut synergistically promote the development of multi-drug-resistance in Escherichia coli.
Combined exposure to duloxetine and chloramphenicol synergistically enhances multidrug resistance in E. coli through upregulation of efflux pumps AcrAB-TolC and MlaFEDB, and mutations in marR.
Metagenomics reveals the temporal dynamics of the rumen resistome and microbiome in goat kids.
The study identified numerous antibiotic resistance genes (ARGs) in the rumen of goat kids, highlighting the dynamic nature of the resistome influenced by age and diet. Key ARGs included RPOB, GYRA, GYRBA, ROB, MDTF, ACRF, ACRB, MGTA, MLS23S, TUFAB, TET44, TET32, APH2-DPRIME, SAT, BRO, TETQ, ERMF, NIMJ, ACI, MEFA, RRSC, RRSH, CAP16S, TETX, LNUC, TETW, TETO, and TET40, which were associated with resistance to various antibiotics such as drugs, MLS, tetracyclines, and others.
Genome mining of Escherichia coli WG5D from drinking water source: unraveling antibiotic resistance genes, virulence factors, and pathogenicity.
The study identifies multiple antibiotic resistance genes in E. coli WG5D, including multidrug efflux pumps and genes conferring resistance to various antibiotics such as fluoroquinolones, cephalosporins, and glycopeptides.
Genomic Dissection of an Enteroaggregative Escherichia coli Strain Isolated from Bacteremia Reveals Insights into Its Hybrid Pathogenic Potential.
The study identifies multiple efflux pump-encoding genes in the E. coli strain EC092, which contribute to its resistance against several antibiotics including tetracycline, trimethoprim, streptomycin, and sulfamethoxazole.
Prevalence and genomic insights of carbapenem resistant and ESBL producing Multidrug resistant Escherichia coli in urinary tract infections.
The study identified multiple AMR genes, including NDM-5, CTX-M-15, TEM-1, and others, in carbapenem-resistant and ESBL-producing multidrug-resistant E. coli isolates from urinary tract infections.
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