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Explore antimicrobial resistance genes from the literature
PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecB
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| mecB | Card DatabaseResFinder Database | 2 | MEROPENEM, ERTAPENEM +12 | Macrococcoides caseolyticum | - | 2009 | 11996 |
| MecB | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 12 | PIPERACILLIN+TAZOBACTAM, MEROPENEM +17 | Macrococcoides caseolyticum +9 | Germany, England|Wales, Australia, Switzerland|Sudan|Czech Republic|Australia, Europe|Czech Republic|Switzerland, Europe | 2014, 2015, 2018, 2020, 2025 | AB498756.1 | BAI83351.1 |
Complete genome sequence of Macrococcus caseolyticus strain JCSCS5402, [corrected] reflecting the ancestral genome of the human-pathogenic staphylococci.
A novel hybrid SCCmec-mecC region in Staphylococcus sciuri.
A novel hybrid SCCmec-mecC region in Staphylococcus sciuri.
A novel hybrid SCCmec-mecC region in Staphylococcus sciuri.
First Staphylococcal Cassette Chromosome mec Containing a mecB-Carrying Gene Complex Independent of Transposon Tn6045 in a Macrococcus canis Isolate from a Canine Infection.
First Staphylococcal Cassette Chromosome mec Containing a mecB-Carrying Gene Complex Independent of Transposon Tn6045 in a Macrococcus caseolyticus Isolate from a Canine Infection.
The study identified a novel SCC mec element containing the mecB gene complex in a methicillin-resistant Macrococcus caseolyticus isolate, which is independent of transposon Tn6045. The mecB gene confers methicillin resistance, and the blaZm gene contributes to penicillin resistance.
Plasmid-Encoded Transferable mecB-Mediated Methicillin Resistance in Staphylococcus aureus.
The study identifies a plasmid-encoded mecB gene in Staphylococcus aureus that confers methicillin resistance, highlighting a potential risk for the spread of β-lactam resistance.
Genome analysis of methicillin resistance in Macrococcus caseolyticus from dairy cattle in England and Wales.
The study identifies mecB and mecD as the primary methicillin resistance determinants in 33 isolates of Macrococcus caseolyticus from dairy cattle in England and Wales.
Characterization of Staphylococcal Cassette Chromosome mec Elements from Methicillin-Resistant Staphylococcus pseudintermedius Infections in Australian Animals.
The study identified six SCC mec types among 77 methicillin-resistant Staphylococcus pseudintermedius isolates from Australian animals, including a novel SCC mec element, ΨSCC mec KW21, which conferred high oxacillin MICs. The study also highlighted the importance of SCC mec typing in understanding the epidemiology of methicillin resistance in veterinary pathogens.
The Novel Macrolide Resistance Genes mef(D), msr(F), and msr(H) Are Present on Resistance Islands in Macrococcus canis, Macrococcus caseolyticus, and Staphylococcus aureus.
The study identifies three novel macrolide resistance genes, mef(D), msr(F), and msr(H), present on resistance islands in Macrococcus canis, Macrococcus caseolyticus, and Staphylococcus aureus. These genes contribute to erythromycin resistance when expressed in S. aureus.
The Porcine Nasal Microbiota with Particular Attention to Livestock-Associated Methicillin-Resistant Staphylococcus aureus in Germany-A Culturomic Approach.
The study identified methicillin-resistant Staphylococcus aureus (MRSA) and other methicillin-resistant staphylococci in porcine nasal microbiota, with mecA and mecB genes responsible for methicillin resistance.
Evidence of in vitro mecB-mediated β-lactam antibiotic resistance transfer to Staphylococcus aureus from Macrococcus psychrotolerans sp. nov., a psychrophilic bacterium from food-producing animals and human clinical specimens.
The study identifies the mecB gene carried on plasmids in Macrococcus psychrotolerans sp. nov. strains, which can be transferred to Staphylococcus aureus via conjugation, leading to β-lactam resistance.
Diversification of the Staphylococcal Cassette Chromosome Through Distinct Mechanisms of Horizontal Transfer.
The study identifies a wide distribution of mec genes across various Staphylococcaceae species, highlighting the diversity of SCC mec elements and their mechanisms of horizontal transfer.
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