Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
macrolide efflux MFS transporter Mef(C)
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| Mef(C) | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 17 | Erythromycin, Tetracycline antibiotic, Macrolide antibiotic, Macrolides, Azithromycin | Photobacterium damselae subsp. damselae, Vibrio ponticus, Escherichia coli, Chryseobacterium sp. POL2, Salmonella enterica, Pasteurella multocida, Acinetobacter, Chryseobacterium, Flavobacterium | Japan, aquaculture, France, China, Germany, Central Germany, Denmark, Portugal, various regions, Sub-Saharan Africa +3 more | 2012, 2018, 2021, 2022, 2024, 2025 | AB571865.1 | BAL43360.1 |
| mef(C)-mph(G) | Reslit | 1 | Azithromycin | Escherichia coli, Salmonella enterica | Europe | 2024 | PRJEB18618|PRJEB21546|PRJEB33169|PRJEB43436|PRJEB43584|PRJEB63535|PRJEB63683 | - |
Novel conjugative transferable multiple drug resistance plasmid pAQU1 from Photobacterium damselae subsp. damselae isolated from marine aquaculture environment.
Research Article
Novel conjugative transferable multiple drug resistance plasmid pAQU1 from Photobacterium damselae subsp. damselae isolated from marine aquaculture environment.
Research Article
Novel conjugative transferable multiple drug resistance plasmid pAQU1 from Photobacterium damselae subsp. damselae isolated from marine aquaculture environment.
Research Article
Novel conjugative transferable multiple drug resistance plasmid pAQU1 from Photobacterium damselae subsp. damselae isolated from marine aquaculture environment.
Research Article
Interplay of a non-conjugative integrative element and a conjugative plasmid in the spread of antibiotic resistance via suicidal plasmid transfer from an aquaculture Vibrio isolate.
Research Article
The study identifies the plasmid pSEA1 and the integrative element Tn 6283, which carry various antibiotic resistance genes including tet(M), mef(C), mph(G), sul2, catII, and bla, facilitating the spread of antibiotic resistance in aquatic environments.
Azithromycin Resistance in Shiga Toxin-Producing Escherichia coli in France between 2004 and 2020 and Detection of mef(C)-mph(G) Genes.
Research Article
The study identifies the mef(C)-mph(G) gene combination as a novel cause of azithromycin resistance in Shiga toxin-producing Escherichia coli (STEC) in France, highlighting the need for monitoring and testing for resistance before therapeutic use.
The Integrative and Conjugative Element ICECspPOL2 Contributes to the Outbreak of Multi-Antibiotic-Resistant Bacteria for Chryseobacterium Spp. and Elizabethkingia Spp.
Research Article
The study identifies the integrative and conjugative element ICE Csp POL2 in the multi-antibiotic-resistant strain Chryseobacterium sp. POL2, which carries several antibiotic resistance genes including those conferring resistance to carbapenems, chloramphenicol, florfenicol, macrolides, tetracycline, and aminoglycosides. The element was found to transfer horizontally to Elizabethkingia species, contributing to the spread of multiple antibiotic resistance genes.
Highly Virulent and Multidrug-Resistant Escherichia coli Sequence Type 58 from a Sausage in Germany.
Research Article
The study identified a highly virulent and multidrug-resistant Escherichia coli strain ST58 from a pork sausage in Germany, carrying resistance genes for beta-lactams, macrolides, streptomycin, sulfonamides, and diaminopyrimidines, along with heavy metal resistance genes.
Comparative Genomic Analysis of Antimicrobial-Resistant Escherichia coli from South American Camelids in Central Germany.
Research Article
The study identified various antimicrobial resistance genes in Escherichia coli isolates from South American camelids in Germany, highlighting the presence of multidrug-resistant strains and the importance of monitoring AMR in these animals.
Comparative Genomic Analysis of Antimicrobial-Resistant Escherichia coli from South American Camelids in Central Germany.
Research Article
The study identified various antimicrobial resistance genes in Escherichia coli isolates from South American camelids in Germany, highlighting the presence of multidrug-resistant strains and the importance of monitoring AMR in these animals.
Macrolide Resistance and In Vitro Potentiation by Peptidomimetics in Porcine Clinical Escherichia coli.
Research Article
The study identifies erm(B), mph(A), mph(B), and mef(C) as acquired macrolide resistance genes in porcine clinical E. coli, demonstrating their association with increased macrolide MICs and the potential of peptidomimetics to potentiate macrolide activity.
Genomic analysis of azithromycin-resistant Salmonella from food animals at slaughter and processing, and retail meats, 2011-2021, United States.
Research Article
Persistence of Marine Bacterial Plasmid in the House Fly (Musca domestica): Marine-Derived Antimicrobial Resistance Genes Have a Chance of Invading the Human Environment.
Research Article
The study shows that the marine bacterial plasmid pAQU1, carrying several antimicrobial resistance genes, can persist in the house fly intestine for up to 5 days, potentially facilitating the transmission of marine-derived antimicrobial resistance genes to the human environment.
Azithromycin resistance in Escherichia coli and Salmonella from food-producing animals and meat in Europe.
Research Article
The study identified several macrolide resistance genes, including mph(A), mph(B), mef(B), erm(B), mef(C)-mph(G), erm(C), erm(42), ere(A), and msr(E)-mph(E), associated with azithromycin resistance in E. coli and Salmonella from food-producing animals and meat in Europe. The study also highlighted the importance of the mph(A) operon structure and its regulatory region in determining azithromycin resistance.
Molecular Characterization of Multidrug-Resistant Escherichia coli from Fecal Samples of Wild Animals.
Research Article
The study identified multiple AMR genes in E. coli isolates from wild animals, including beta-lactamases (bla TEM-1B, bla CTX-M-65, bla CTX-M-55, bla EC-1982), aminoglycoside resistance genes (aac(3)-IIa, aadA2, aadA5, ant(3")-Ia, aph(3")-Ib, aph(3′)-Ia, aph(6)-Id), tetracycline resistance genes (tetB, tetA), trimethoprim resistance genes (dfrA17, dfrA1, dfrA5, dfrA12), sulfonamide resistance genes (sul1, sul2, sul3), macrolide/lincosamide/streptogramin resistance genes (mphB, lnuF, ermC, mefC), quinolone resistance genes (qnrB19, qnrB5, qnrS1, qnrS2), and others. Additionally, point mutations in gyrA, parC, and parE were associated with fluoroquinolone resistance.
Antimicrobial Resistance in Pasteurella multocida Isolates from Bovine Mastitis Can Be Associated with Multidrug-Resistance-Mediating Integrative and Conjugative Elements (ICEs).
Research Article
Geographics and bacterial networks differently shape the acquired and latent global sewage resistomes.
Research Article
The study identifies several AMR genes, including aph(6)-id_2, mef(c), mef(b), mph(e), mph(g), msr(d), lnu(b), lnu(d), aadA, ant(6)-Ia, blaCTX-M, blaTEM, blaSHV, blaOXA, qnrS1, mcr-1, and vanA, which are associated with resistance to various antibiotics such as aminoglycosides, macrolides, lincosamides, beta-lactams, fluoroquinolones, polymyxins, and glycopeptides.
No comments yet. Be the first to comment!