mef(D)

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macrolide efflux protein

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to mef(D)

AMR Rules

Browse AMR rules for mef(D)

Validation StatusConfirmed2+ DBs

Overview

Mechanism: antibiotic efflux
Validation Method: cloning in S. aureus + MIC testing
Drug Classes: Erythromycin, Macrolide antibiotic
Organisms: Staphylococcus aureus, Macrococcus canis, Macrococcoides canis
Geographic Location: Switzerland|Sudan|Czech Republic|Australia
Papers: 1
Databases: Card DatabaseReference Gene CatalogReslit

Papers1

The Novel Macrolide Resistance Genes mef(D), msr(F), and msr(H) Are Present on Resistance Islands in Macrococcus canis, Macrococcus caseolyticus, and Staphylococcus aureus.

Research Article

PMID 32122903 · 2020

The study identifies three novel macrolide resistance genes, mef(D), msr(F), and msr(H), present on resistance islands in Macrococcus canis, Macrococcus caseolyticus, and Staphylococcus aureus. These genes contribute to erythromycin resistance when expressed in S. aureus.

Gene Information

Gene Name: mef(D)
Allele: Mef(D)
Encodes: macrolide efflux protein
Source Database: Reslit
Confers Resistance To: erythromycin
Organisms Tested In: • Staphylococcus aureus
• Macrococcus canis
Geographic Location: Switzerland|Sudan|Czech Republic|Australia
Validation Method: cloning in S. aureus + MIC testing
Sequence Accession: MN728681|MN728682|BK011995|CP047363|CP047364|CP047365|CP047361|CP047362

The Novel Macrolide Resistance Genes mef(D), msr(F), and msr(H) Are Present on Resistance Islands in Macrococcus canis, Macrococcus caseolyticus, and Staphylococcus aureus.

Research Article

PMID 32122903 · 2020

Gene Information

Gene Name: mef(D)
Allele: Mef(D)
Encodes: macrolide efflux MFS transporter Mef(D)
Source Database: Reference Gene Catalog
Mechanism: antibiotic efflux
Confers Resistance To: ERYTHROMYCIN
Organisms Tested In: • Macrococcoides canis
Sequence Accession: MN728681.1
Protein Accession: QHW12307.1
Notes: ARO:3005089

The Novel Macrolide Resistance Genes mef(D), msr(F), and msr(H) Are Present on Resistance Islands in Macrococcus canis, Macrococcus caseolyticus, and Staphylococcus aureus.

Research Article

PMID 32122903 · 2020

Gene Information

Gene Name: mef(D)
Allele: Mef(D)
Encodes: macrolide efflux MFS transporter Mef(D)
Source Database: Card Database
Mechanism: antibiotic efflux
Confers Resistance To: ERYTHROMYCIN
Organisms Tested In: • Macrococcoides canis
Sequence Accession: MN728681.1
Protein Accession: QHW12307.1
Notes: ARO:3005089

PMID 32122903

Gene Information

Gene Name: mef(D)
Allele: mef(D)
Encodes: major facilitator superfamily (MFS) antibiotic efflux pump
Source Database: Card Database
Mechanism: antibiotic efflux
Confers Resistance To: ERYTHROMYCINMACROLIDE ANTIBIOTIC
Organisms Tested In: • Macrococcoides canis
Sequence Accession: MN728681.1
Protein Accession: QHW12307.1
Notes: ARO:3005089

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mef(D)

View on PubMed

macrolide efflux protein

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to mef(D)

AMR Rules

Browse AMR rules for mef(D)

Validation StatusConfirmed2+ DBs

Overview

Mechanism: antibiotic efflux
Validation Method: cloning in S. aureus + MIC testing
Drug Classes: Erythromycin, Macrolide antibiotic
Organisms: Staphylococcus aureus, Macrococcus canis, Macrococcoides canis
Geographic Location: Switzerland|Sudan|Czech Republic|Australia
Papers: 1
Databases: Card DatabaseReference Gene CatalogReslit

Papers1

The Novel Macrolide Resistance Genes mef(D), msr(F), and msr(H) Are Present on Resistance Islands in Macrococcus canis, Macrococcus caseolyticus, and Staphylococcus aureus.

Research Article

PMID 32122903 · 2020

Gene Information

Gene Name: mef(D)
Allele: Mef(D)
Encodes: macrolide efflux protein
Source Database: Reslit
Confers Resistance To: erythromycin
Organisms Tested In: • Staphylococcus aureus
• Macrococcus canis
Geographic Location: Switzerland|Sudan|Czech Republic|Australia
Validation Method: cloning in S. aureus + MIC testing
Sequence Accession: MN728681|MN728682|BK011995|CP047363|CP047364|CP047365|CP047361|CP047362

The Novel Macrolide Resistance Genes mef(D), msr(F), and msr(H) Are Present on Resistance Islands in Macrococcus canis, Macrococcus caseolyticus, and Staphylococcus aureus.

Research Article

PMID 32122903 · 2020

Gene Information

Gene Name: mef(D)
Allele: Mef(D)
Encodes: macrolide efflux MFS transporter Mef(D)
Source Database: Reference Gene Catalog
Mechanism: antibiotic efflux
Confers Resistance To: ERYTHROMYCIN
Organisms Tested In: • Macrococcoides canis
Sequence Accession: MN728681.1
Protein Accession: QHW12307.1
Notes: ARO:3005089

The Novel Macrolide Resistance Genes mef(D), msr(F), and msr(H) Are Present on Resistance Islands in Macrococcus canis, Macrococcus caseolyticus, and Staphylococcus aureus.

Research Article

PMID 32122903 · 2020

Gene Information

Gene Name: mef(D)
Allele: Mef(D)
Encodes: macrolide efflux MFS transporter Mef(D)
Source Database: Card Database
Mechanism: antibiotic efflux
Confers Resistance To: ERYTHROMYCIN
Organisms Tested In: • Macrococcoides canis
Sequence Accession: MN728681.1
Protein Accession: QHW12307.1
Notes: ARO:3005089

PMID 32122903

Gene Information

Gene Name: mef(D)
Allele: mef(D)
Encodes: major facilitator superfamily (MFS) antibiotic efflux pump
Source Database: Card Database
Mechanism: antibiotic efflux
Confers Resistance To: ERYTHROMYCINMACROLIDE ANTIBIOTIC
Organisms Tested In: • Macrococcoides canis
Sequence Accession: MN728681.1
Protein Accession: QHW12307.1
Notes: ARO:3005089

Comments (0)

No comments yet. Be the first to comment!

mef(D)

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mef(D)

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