mef(a/e)

efflux pump

Overview

Validation Method
multiplex PCR and reverse line blot hybridization assay
Drug Classes
macrolides
Organisms
Streptococcus agalactiae
Geographic Location
Asia|Australasia
Papers
1
Databases
Reslit
Papers1
1

Simultaneous detection of nine antibiotic resistance-related genes in Streptococcus agalactiae using multiplex PCR and reverse line blot hybridization assay.

PMID 16377687 · 2006

The study developed a multiplex PCR and reverse line blot hybridization assay to detect nine antibiotic resistance-related genes in Streptococcus agalactiae, including erm(B), erm(A/TR), mef(A/E), tet(M), tet(O), aphA-3, aad-6, int-Tn, and mreA. These genes were found to be associated with resistance to macrolides, lincosamides, streptogramin B, tetracyclines, and aminoglycosides.

Gene Information

Gene Name
mef(a/e)
Allele
mef(A/E)
Encodes
efflux pump
Source Database
Reslit
Confers Resistance To
macrolides
Organisms Tested In
Streptococcus agalactiae
Geographic Location
Asia|Australasia
Validation Method
multiplex PCR and reverse line blot hybridization assay
Sequence Accession
DQ103589
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