mepA

MATE family efflux pump

Validation StatusCandidate

Overview

Validation Method: overexpression in wild-type background
Drug Classes: tigecycline, ethidium bromide, tetraphenylphosphonium bromide, dmg-mino, dmg-dmdot
Organisms: Staphylococcus aureus
Papers: 1
Databases: Reslit

Papers1

A novel MATE family efflux pump contributes to the reduced susceptibility of laboratory-derived Staphylococcus aureus mutants to tigecycline.

Gene Name: mepA
Allele: MepA
Encodes: MATE family efflux pump
Source Database: Reslit
Confers Resistance To: tigecyclineethidium bromidetetraphenylphosphonium bromidedmg-minodmg-dmdot
Organisms Tested In: • Staphylococcus aureus
Validation Method: overexpression in wild-type background

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