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MexG

resistance-nodulation-cell division (RND) antibiotic efflux pump

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to MexG

Browse AMR rules for MexG

Validation StatusEstablished

Overview

Mechanism: antibiotic efflux
Drug Classes: FLUOROQUINOLONE ANTIBIOTIC, TETRACYCLINE ANTIBIOTIC, DISINFECTING AGENTS AND ANTISEPTICS, tetracycline, ticarcillin clavulanic acid, piperacillin tazobactam, ceftazidime, cefepime, meropenem, imipenem, tobramycin, ciprofloxacin, levofloxacin, fluoroquinolones
Organisms: Pseudomonas aeruginosa PAO1, Pseudomonas aeruginosa
Papers: 4
Databases: Card Database
Mutations: 4

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
P51S	-	-	Pseudomonas aeruginosa	tetracyclineticarcillin clavulanic acid	Reslit	Candidate
G195D	-	-	Pseudomonas aeruginosa	piperacillin tazobactamceftazidimecefepime+4 more	Reslit	Candidate
-	C151T	-	Pseudomonas aeruginosa	ciprofloxacinlevofloxacin	Reslit	Candidate
-	C5A	-	Pseudomonas aeruginosa	fluoroquinolones	Reslit	Candidate

Papers4

1

Gene Information

Gene Name: MexG
Allele: MexG
Encodes: resistance-nodulation-cell division (RND) antibiotic efflux pump
Source Database: Card Database
Mechanism: antibiotic efflux
Confers Resistance To: FLUOROQUINOLONE ANTIBIOTICTETRACYCLINE ANTIBIOTICDISINFECTING AGENTS AND ANTISEPTICS
Organisms Tested In: • Pseudomonas aeruginosa PAO1
Sequence Accession: AE004091.2
Protein Accession: AAG07592.1
Notes: ARO:3000806

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