Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
multidrug efflux RND transporter periplasmic adaptor subunit MexX
Overview
| Candidate |
| K329Q | - | - | - | Ciprofloxacin|Norfloxacin|Imipenem|Meropenem | Reslit | Candidate |
| - | - | Pseudomonas aeruginosa | Fluoroquinolones | Reslit | Candidate |
| - | - | Pseudomonas aeruginosa | Fluoroquinolones | Reslit | Candidate |
| - | - | Pseudomonas aeruginosa | Fluoroquinolones | Reslit | Candidate |
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| MexX | Card DatabaseReference Gene CatalogReslit | 9 | EFFLUX, Aminoglycoside +7 | Pseudomonas aeruginosa PAO1 +1 | India, Denmark|United States, New Zealand|Australia, Europe | 1999, 2012, 2018, 2022 | AF147719.1 | AAF14522.1 |
| mex X | Reslit | 1 | Fluoroquinolone, Aminoglycoside +1 | Pseudomonas aeruginosa | Romania | 2023 | - | - |
| mexX | Card Database | 1 | - | Pseudomonas aeruginosa PAO1 | - | - | AB015853.1 | BAA34299.1 |
Characterization of a Pseudomonas aeruginosa efflux pump contributing to aminoglycoside impermeability.
MexXY multidrug efflux system of Pseudomonas aeruginosa.
The study characterizes the MexXY multidrug efflux system in Pseudomonas aeruginosa, highlighting its role in aminoglycoside resistance. It also identifies related efflux systems in other bacteria such as AcrD in E. coli, AmrAB-OprA in B. pseudomallei, and AdeABC in A. baumannii.
Application of six multiplex PCR's among 200 clinical isolates of Pseudomonas aeruginosa for the detection of 20 drug resistance encoding genes.
The study identified several beta-lactamase genes (blaTem, blaOXA, blaCTX-M-15, blaVim, blaGes, blaVeb, blaDIM, AmpC) and efflux pump genes (MexA, MexB, OprM, MexC, MexD, OprJ, MexX, MexY, OprN, nfxB, MexR, OprD) in Pseudomonas aeruginosa clinical isolates, highlighting their roles in mediating resistance to various antibiotics.
Pseudomonas aeruginosa transcriptome during human infection.
The study identifies several P. aeruginosa genes that are induced during human infections and are associated with antibiotic resistance mechanisms, including efflux pumps, β-lactamases, and other resistance determinants.
Expression of Pseudomonas aeruginosa Antibiotic Resistance Genes Varies Greatly during Infections in Cystic Fibrosis Patients.
The study identified that the expression of ampC and mexX genes in Pseudomonas aeruginosa varies greatly during infections in cystic fibrosis patients, contributing to antibiotic resistance.
Combination of phage therapy and cefiderocol to successfully treat Pseudomonas aeruginosa cranial osteomyelitis.
The study identifies the presence of the blaGES-1 gene and MDR efflux pumps MexD and MexX in multidrug-resistant P. aeruginosa isolates, which contribute to resistance against various β-lactam antibiotics. Phage therapy in combination with cefiderocol was successful in treating the infection.
Antibiotic resistance in plant growth promoting bacteria: A comprehensive review and future perspectives to mitigate potential gene invasion risks.
This review highlights the prevalence of antibiotic resistance genes (ARGs) in plant growth-promoting bacteria (PGPB) and emphasizes the potential risks of ARG dissemination through biofertilizers. Key findings include the identification of various ARGs such as bacA, fosB, ermD, bl2a, vanSA, cat, acrD, mexF, mexD, mexW, mexE, mexY, mexX, mexZ, mexR, mexA, mexB, mexC, mexD, mexE, and mexF, which confer resistance to multiple antibiotics.
Uncovering the Resistance Mechanisms in Extended-Drug-Resistant Pseudomonas aeruginosa Clinical Isolates: Insights from Gene Expression and Phenotypic Tests.
The study identified bla GES-2, bla OXA48-like, bla NDM, bla SPM, and bla VIM as the main carbapenemase genes in MDR P. aeruginosa isolates. Overexpression of mex efflux pumps, particularly mex C, was strongly associated with multidrug resistance.
Expression in Escherichia coli of a new multidrug efflux pump, MexXY, from Pseudomonas aeruginosa.
Expression in Escherichia coli of a new multidrug efflux pump, MexXY, from Pseudomonas aeruginosa.
No comments yet. Be the first to comment!
© 2026 ResLit. Data sourced from PubMed literature analysis.
Built for antimicrobial resistance research