Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
lytic transglycosylase
Overview
| Candidate |
Slt, MltD, and MltG of Pseudomonas aeruginosa as Targets of Bulgecin A in Potentiation of β-Lactam Antibiotics.
The study identifies Slt, MltD, and MltG as targets of bulgecin A, showing that their inhibition enhances the potency of β-lactam antibiotics by disrupting cell wall repair and promoting bulge formation and lysis in Pseudomonas aeruginosa.
Identification of Drug Resistance Determinants in a Clinical Isolate of Pseudomonas aeruginosa by High-Density Transposon Mutagenesis.
The study identifies several nonessential genes involved in β-lactam resistance in Pseudomonas aeruginosa, including ampC, mltG, mepM1, amgK, and ygfB, which contribute to the induction of ampC expression and resistance against meropenem and cefepime.
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