mmp

multidrug and toxic compound extrusion (MATE) family protein

Validation StatusCandidate

Overview

Validation Method: Phenotype MicroArray (PM) and MIC determination
Drug Classes: Capreomycin, Amikacin, Kanamycin, Phleomycin, Bleomycin, Sulfamethazine, Sulfadiazine, Sulfathiazole, Sulfamethoxazole, Sulfachloropyridazine, Sulfamonomethoxine
Organisms: Mycobacterium smegmatis
Papers: 1
Databases: Reslit

Papers1

Characterization of the MSMEG_2631 Gene (mmp) Encoding a Multidrug and Toxic Compound Extrusion (MATE) Family Protein in Mycobacterium smegmatis and Exploration of Its Polyspecific Nature Using Biolog Phenotype MicroArray

PMID 23292779 · 2013

The study identifies the mmp gene in Mycobacterium smegmatis as encoding a Na+-dependent MATE family multidrug efflux pump that contributes to intrinsic resistance against various antibiotics, DNA-damaging chemicals, and disinfectants.

Gene Information

Gene Name: mmp
Allele: mmp
Encodes: multidrug and toxic compound extrusion (MATE) family protein
Source Database: Reslit
Confers Resistance To: CapreomycinAmikacinKanamycinPhleomycinBleomycinSulfamethazineSulfadiazineSulfathiazoleSulfamethoxazoleSulfachloropyridazineSulfamonomethoxine
Organisms Tested In: • Mycobacterium smegmatis
Validation Method: Phenotype MicroArray (PM) and MIC determination

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mmp

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