Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
flavokinase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| mreA | Card DatabaseReslit | 6 | Macrolide, Clindamycin +13 | Streptococcus agalactiae +2 | Brazil, China, Mexico, Haikou, China | 2001, 2022, 2023, 2025 | U92073 |
| AAB64408.1 |
| mre(A) | ResFinder DatabaseReslit | 4 | Erythromycin, Clindamycin +5 | Streptococcus agalactiae | Denmark, Swiss Canton Tessin|various herds|Switzerland, Thailand | 1997, 2021, 2023, 2025 | PRJEB43628|PRJEB38759 | - |
Macrolide Resistance Gene mreA of Streptococcus agalactiae Encodes a Flavokinase.
The mreA gene from Streptococcus agalactiae COH31 γ/δ encodes a flavokinase that confers broad-spectrum resistance to various antibiotics and compounds when cloned in E. coli, but not in Enterococcus faecalis.
Molecular Identification of Invasive Non-typeable Group B Streptococcus Isolates From Denmark (2015 to 2017).
The study identified several AMR genes associated with erythromycin and clindamycin resistance in invasive non-typeable Group B Streptococcus isolates from Denmark, including mre(A), erm(B), erm(A), mef(A), msr(D), and Isa(C).
Bacteriocin Producing Streptococcus agalactiae Strains Isolated from Bovine Mastitis in Brazil.
The study identified the mreA and mprF genes in Streptococcus agalactiae strains, which confer resistance to erythromycin, azithromycin, spiramycin, and cationic antimicrobial peptides.
Molecular Epidemiology of Group B Streptococcus Isolates from Pregnant Women with Premature Rupture of Membranes in Fuzhou, China.
The study identified several AMR genes in GBS isolates from pregnant women with PROM in Fuzhou, China, including mreA, ermB, mefA, mefE, ermA, ermTR, tetM, and tetK, which are associated with resistance to erythromycin and tetracycline.
Elucidation of the Bovine Intramammary Bacteriome and Resistome from healthy cows of Swiss dairy farms in the Canton Tessin.
The study identified the presence of the tetracycline resistance gene tetK in Mammaliicoccus sciuri isolates, which was associated with tetracycline resistance. The gene was found on small plasmids, suggesting a potential mechanism for horizontal gene transfer.
Genomic profiling of Streptococcus agalactiae (Group B Streptococcus) isolates from pregnant women in northeastern Mexico: clonal complexes, virulence factors, and antibiotic resistance.
The study identified the presence of mreA and tetM genes in all 51 S. agalactiae isolates, indicating widespread macrolide and tetracycline resistance. The mreA gene was found in 100% of isolates, while tetM was present in 60.1% of isolates.
Molecular epidemiology and antibiotic resistance of group B Streptococcus in pregnant women and neonates from Haikou, China: implications for vaccine development and antimicrobial stewardship.
The study identified high rates of tetracycline (89.1%) and clindamycin (55.1%) resistance in GBS strains from Haikou, China. Key resistance genes included mreA, ermB, tetM, catQ, cat(pC194), ant(6)-Ia, aph(3')-III, and aac(6')-aph(2'').
Diversity and antimicrobial resistance among bacterial isolates from finfish aquaculture in Thailand.
The study identified high levels of antimicrobial resistance in bacterial isolates from finfish aquaculture in Thailand, with particular emphasis on beta-lactam, tetracycline, and fluoroquinolone resistance in Gram-negative bacteria, and beta-lactam, macrolide, fluoroquinolone, and peptide resistance in Gram-positive bacteria. Unique resistance gene families, such as the SMR efflux pump and OXA beta-lactamase, were found in Aeromonas spp. and V. vulnificus.
Cloning and characterization of a novel macrolide efflux gene, mreA, from Streptococcus agalactiae.
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