Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| A39T | - | - | Neisseria gonorrhoeae | Triton X-100|erythromycin|azithromycin|kanamycin|progesterone|CRAMP-38 | Reslit | Candidate |
| E202G | - | - | Neisseria gonorrhoeae | Triton X-100|erythromycin|azithromycin|kanamycin|progesterone|CRAMP-38 | Reslit | Candidate |
| G45D | - | disrupts the DNA-binding domain of the MtrR repressor | Neisseria gonorrhoeae |
ceftriaxone|cefixime |
Reslit |
| Candidate |
Clinically relevant mutations that cause derepression of the Neisseria gonorrhoeae MtrC-MtrD-MtrE Efflux pump system confer different levels of antimicrobial resistance and in vivo fitness.
Confers higher in vitro resistance and in vivo fitness compared to other mtrR mutations
Genetics of chromosomally mediated intermediate resistance to ceftriaxone and cefixime in Neisseria gonorrhoeae.
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