nfsB

Validation StatusCandidate

Overview

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
G192A	G575C	-	Neisseria gonorrhoeae	nitrofurantoin	Reslit	Candidate

Papers1

Use of nfsB, encoding nitroreductase, as a reporter gene to determine the mutational spectrum of spontaneous mutations in Neisseria gonorrhoeae.

Mutations in nfsB lead to loss of nitroreductase activity, resulting in nitrofurantoin resistance.