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organic hydroperoxide reductase
Overview
Resistance to organic hydroperoxides requires ohr and ohrR genes in Sinorhizobium meliloti.
The study identifies ohr and ohrR genes in Sinorhizobium meliloti that are crucial for resistance to organic hydroperoxides. Ohr is essential for surviving organic peroxide stress, while OhrR acts as a transcriptional repressor regulating ohr expression.
Characterization of the organic hydroperoxide resistance system of Brucella abortus 2308.
The study characterizes the organic hydroperoxide resistance system in Brucella abortus 2308, identifying Ohr as a detoxifier of organic hydroperoxides and OhrR as a transcriptional repressor of ohr and ohrR.
Inactivation of the organic hydroperoxide stress resistance regulator OhrR enhances resistance to oxidative stress and isoniazid in Mycobacterium smegmatis.
Inactivation of OhrR in Mycobacterium smegmatis leads to increased expression of Ohr, enhancing resistance to oxidative stress and isoniazid.
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