Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
oleandomycin glycosyltransferase OleD
Overview
Probing the breadth of macrolide glycosyltransferases: in vitro remodeling of a polyketide antibiotic creates active bacterial uptake and enhances potency.
Research Article
Probing the breadth of macrolide glycosyltransferases: in vitro remodeling of a polyketide antibiotic creates active bacterial uptake and enhances potency.
Research Article
Intracellularly driven chemical modifications of antimicrobial secondary metabolites: Potent mechanisms of self-resistance.
Review
The paper reviews various enzymatic modifications used by natural product (NP) producers to develop self-resistance against their own antimicrobial secondary metabolites, including phosphorylation, acylation, deglycosylation, glycosylation, redox reactions, hydrolysis, and dual modifications.
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