oppD

oligopeptide ABC transporter ATP-binding protein

Validation StatusCandidate

Overview

Validation Method: transcriptomic and proteomic analysis
Drug Classes: Amikacin, Aminoglycoside
Organisms: Salmonella enteritidis, Escherichia coli
Geographic Location: China
Papers: 2
Databases: Reslit
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
L245F	-	-	Escherichia coli	Aminoglycoside	Reslit	Candidate

Papers2

Increased growth rate and amikacin resistance of Salmonella enteritidis after one-month spaceflight on China's Shenzhou-11 spacecraft.

PMID 30912318 · 2019

The spaceflight strain of Salmonella enteritidis showed increased amikacin resistance due to downregulation of the oppA gene encoding the oligopeptide transporter protein OppA.

Gene Information

Gene Name: oppD
Allele: oppD
Encodes: oligopeptide ABC transporter ATP-binding protein
Source Database: Reslit
Confers Resistance To: Amikacin
Organisms Tested In: • Salmonella enteritidis
Geographic Location: China
Validation Method: transcriptomic and proteomic analysis
Sequence Accession: CP033089|CP033090|SAMN10250723|SAMN10251062|SAMN10371527|SAMN10371528|PXD011651

Browse AMR Genes

oppD

Mutations

Gene Information