Browse AMR Genes

Explore antimicrobial resistance genes from the literature

pbp2a

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Browse AMR rules for pbp2a

Validation StatusCandidate

Overview

Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
E63K	-	reduced penicillin susceptibility	Streptococcus agalactiae	penicillin	Reslit	Candidate

Papers1

1

Genetic Heterogeneity in pbp Genes among Clinically Isolated Group B Streptococci with Reduced Penicillin Susceptibility.

PMID 18809936 · 2008

Mutations in pbp2a are associated with reduced penicillin susceptibility

Mutation Information

Protein Change: E63K
Organisms: Streptococcus agalactiae
Confers Resistance To: penicillin
Effect on Function: reduced penicillin susceptibility
Source Database: Reslit