pgmA

phosphoglucomutase

Validation StatusCandidate

Overview

Validation Method: mutant analysis and complementation
Drug Classes: Polymyxin b
Organisms: Yersinia pestis
Papers: 1
Databases: Reslit

Papers1

Phosphoglucomutase of Yersinia pestis is required for autoaggregation and polymyxin B resistance.

PMID 20028810 · 2010

The study identifies pgmA as a gene required for autoaggregation and polymyxin B resistance in Yersinia pestis. Deletion of pgmA leads to increased sensitivity to polymyxin B, and this defect can be restored by complementation with pgmA.

Gene Information

Gene Name: pgmA
Allele: pgmA
Encodes: phosphoglucomutase
Source Database: Reslit
Confers Resistance To: Polymyxin b
Organisms Tested In: • Yersinia pestis
Validation Method: mutant analysis and complementation

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pgmA

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