ppm1

Overview

Drug Classes: Ampicillin|Imipenem|Meropenem|Rifampicin|Vancomycin
Organisms: Streptomyces coelicolor
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
E218V	A654T	increased susceptibility to multiple antibiotics	Streptomyces coelicolor	Ampicillin\|Imipenem\|Meropenem\|Rifampicin\|Vancomycin	Reslit	Candidate

Papers1

Streptomyces coelicolor strains lacking polyprenol phosphate mannose synthase and protein O-mannosyl transferase are hyper-susceptible to multiple antibiotics.

PMID 29458553 · 2018

ppm1 mutants show increased susceptibility to multiple antibiotics

Mutation Information

ppm1: p.E218V / c.A654T

Protein Change: E218V
Nucleotide Change: A654T
Organisms: Streptomyces coelicolor
Confers Resistance To: Ampicillin|Imipenem|Meropenem|Rifampicin|Vancomycin
Effect on Function: increased susceptibility to multiple antibiotics
Source Database: Reslit

Browse AMR Genes

ppm1

Mutations

Mutation Information