pstB

phosphate import ATP-binding protein

Validation StatusCandidate

Overview

Validation Method: machine learning model interpretation
Drug Classes: Polymyxin, Amikacin, Gentamicin|Amikacin
Organisms: Klebsiella pneumoniae, Pseudomonas aeruginosa
Papers: 3
Databases: Reslit
Mutations: 2

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
E89Q	-	-	Pseudomonas aeruginosa	AmikacinGentamicin\|Amikacin	Reslit	Candidate
R87C	-	-	Pseudomonas aeruginosa	Amikacin	Reslit	Candidate

Papers3

Predicting Phenotypic Polymyxin Resistance in Klebsiella pneumoniae through Machine Learning Analysis of Genomic Data.

PMID 32457240 · 2020

The study identifies several genes associated with polymyxin resistance in Klebsiella pneumoniae using machine learning analysis of genomic data, including known resistance determinants and potential novel genes.

Gene Information

Gene Name: pstB
Allele: pstB
Encodes: phosphate import ATP-binding protein
Source Database: Reslit
Confers Resistance To: Polymyxin
Organisms Tested In: • Klebsiella pneumoniae
Validation Method: machine learning model interpretation

Browse AMR Genes

pstB

Mutations

Gene Information