qac

quaternary ammonium compound efflux pump

Validation StatusCandidate

Overview

Validation Method: plasmid analysis
Drug Classes: quaternary ammonium compound
Organisms: Salmonella enterica serovar Choleraesuis
Geographic Location: Europe
Papers: 1
Databases: Reslit

Papers1

The genome sequence of Salmonella enterica serovar Choleraesuis, a highly invasive and resistant zoonotic pathogen.

PMID 15781495 · 2005

The study identifies multiple antimicrobial resistance genes on plasmids pSC138 and pSCV50 in Salmonella enterica serovar Choleraesuis SC-B67, including blaTEM-1, blaCMY-2, tetRA, strA, aadA2, sulI, sulII, catI, cmlA, aph, sat, mef, mer, ebr, qac, and blaTEM-67. Additionally, mutations in the chromosomal genes gyrA and parC, along with the inactivation of acrR, contribute to ciprofloxacin resistance.

Gene Information

Gene Name: qac
Allele: qac
Encodes: quaternary ammonium compound efflux pump
Source Database: Reslit
Confers Resistance To: quaternary ammonium compound
Organisms Tested In: • Salmonella enterica serovar Choleraesuis
Geographic Location: Europe
Validation Method: plasmid analysis
Sequence Accession: NC_003143|NC_004061|NC_002528|NC_004741|NC_004631|NC_004545|NC_000913|NC_004431|NC_004088|NC_003198|NC_002695|NC_002655|NC_004344|NC_004337|NC_003197

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