qnrS
quinolone resistance protein
NCBI Pathogen Isolates
Bacterial genomes carrying this gene
NCBI Reference Gene Catalog
Known alleles and reference sequences
UniProt
Protein entries specific to qnrS
AMR Rules
Browse AMR rules for qnrS
Validation StatusCandidate
Overview
- Validation Method
- cloning and transformation followed by MIC testing
- Drug Classes
- quinolones
- Organisms
- Escherichia coli HB101, Shigella flexneri 2b
- Geographic Location
- Japan
- Papers
- 1
- Databases
- Reslit
Papers1
1
Cloning of a Novel Gene for Quinolone Resistance from a Transferable Plasmid in Shigella flexneri 2b.
A novel quinolone resistance gene, qnrS, was cloned from a transferable plasmid in Shigella flexneri 2b. The gene shows 59% amino acid identity with Qnr and confers low-level quinolone resistance when expressed in E. coli HB101.
Gene Information
- Gene Name
- qnrS
- Allele
- qnrS
- Encodes
- quinolone resistance protein
- Source Database
- Reslit
- Confers Resistance To
- quinolones
- Organisms Tested In
- • Escherichia coli HB101• Shigella flexneri 2b
- Geographic Location
- Japan
- Validation Method
- cloning and transformation followed by MIC testing
- Sequence Accession
- AB187515
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