Browse AMR Genes

Explore antimicrobial resistance genes from the literature

ramA

General Bacterial Porin with reduced permeability to beta-lactams;resistance-nodulation-cell division (RND) antibiotic efflux pump

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to ramA

Browse AMR rules for ramA

Validation StatusEstablished

Overview

Mechanism: antibiotic efflux;reduced permeability to antibiotic
Drug Classes: Colistin, Tigecycline, Piperacillin/tazobactam|Ceftazidime|Levofloxacin|Tigecycline|Doxycycline|Minocycline, Fluoroquinolones
Organisms: Enterobacter cloacae, Klebsiella pneumoniae, Enterobacter hormaechei, Klebsiella quasipneumoniae, Salmonella enterica
Papers: 5
Databases: Card Database
Mutations: 5

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
H38Y	-	-	Klebsiella pneumoniae, Klebsiella quasipneumoniae	Colistin	Reslit	Candidate
E83A	-	increased expression	Enterobacter cloacae, Enterobacter hormaechei	Colistin	Reslit	Candidate
W37K	-	-	Enterobacter cloacae	Tigecycline