Browse AMR Genes

Explore antimicrobial resistance genes from the literature

rfaF

lipopolysaccharide (LPS) core heptose transferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to rfaF

Browse AMR rules for rfaF

Validation StatusCandidate

Overview

Validation Method: knockout and complementation experiments with MIC testing
Drug Classes: Amoxicillin, Tetracycline, Clarithromycin, Chloramphenicol, Amoxicillin|Tetracycline|Clarithromycin|Chloramphenicol
Organisms: Helicobacter pylori 11,637, H. pylori, H. pylori 11,637, H. pylori MDR, Helicobacter pylori, Escherichia coli
Papers: 2
Databases: Reslit
Mutations: 10

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
S250N	-	-	Helicobacter pylori	Amoxicillin\|Tetracycline\|Clarithromycin\|Chloramphenicol	Reslit	Candidate
P192L	-	-	Helicobacter pylori	Amoxicillin\|Tetracycline\|Clarithromycin\|Chloramphenicol	Reslit	Candidate
I59A	-	-	Helicobacter pylori	Amoxicillin\|Tetracycline\|Clarithromycin\|Chloramphenicol