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Explore antimicrobial resistance genes from the literature
RmtH family 16S rRNA (guanine(1405)-N(7))-methyltransferase
Overview
Novel 16S rRNA methyltransferase RmtH produced by Klebsiella pneumoniae associated with war-related trauma.
Novel 16S rRNA methyltransferase RmtH produced by Klebsiella pneumoniae associated with war-related trauma.
Novel 16S rRNA methyltransferase RmtH produced by Klebsiella pneumoniae associated with war-related trauma.
Novel 16S rRNA Methyltransferase RmtH Produced by Klebsiella pneumoniae Associated with War-Related Trauma.
The study identifies a novel 16S rRNA methyltransferase, RmtH, which confers high-level resistance to all aminoglycosides tested, including gentamicin, tobramycin, amikacin, and arbekacin in Klebsiella pneumoniae.
Novel 16S rRNA methyltransferase RmtH produced by Klebsiella pneumoniae associated with war-related trauma.
Aminoglycoside Resistance: The Emergence of Acquired 16S Ribosomal RNA Methyltransferases.
The paper discusses the emergence and characteristics of acquired 16S ribosomal RNA methyltransferases (16S-RMTases) that confer resistance to aminoglycosides, particularly in gram-negative bacteria. It highlights the importance of these genes in multidrug-resistant organisms and their association with other resistance mechanisms such as carbapenemases.
Expansion of acquired 16S rRNA methytransferases along with CTX-M-15, NDM and OXA-48 within three sequence types of Escherichia coli from northeast India.
The study identified ten different 16S rRNA methyltransferase genes (rmtA, rmtB, rmtC, rmtD, rmtE, rmtF, rmtG, rmtH, armA, npmA) along with CTX-M-15, NDM, and OXA-48 beta-lactamases in three sequence types of Escherichia coli from northeast India.
The resistomes of Mycobacteroides abscessus complex and their possible acquisition from horizontal gene transfer.
The study identifies numerous AMR genes in Mycobacteroides abscessus complex, highlighting the widespread presence of resistance to multiple antibiotic classes, including beta-lactams, aminoglycosides, glycopeptides, and others. Key findings include the detection of beta-lactamases like blaLAP-1 and blaTLA-2, 23S rRNA methyltransferases such as erm(33), erm(43), and erm(44), and various aminoglycoside modifying enzymes. Additionally, vancomycin resistance genes like vanA, vanB, and vanC were identified, along with efflux pump genes contributing to multidrug resistance.
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