rpfC

Resuscitation-promoting factor C

Validation StatusCandidate

Overview

Mechanism: confers resistance to beta-lactams
Validation Method: core-SNV analysis and MIC testing
Drug Classes: Amoxicillin, Meropenem, Amoxicillin|Meropenem
Organisms: Mycobacterium tuberculosis
Geographic Location: Portugal
Papers: 1
Databases: Reslit
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
H16R	-	-	Mycobacterium tuberculosis	Amoxicillin\|Meropenem	Reslit	Candidate

Papers1

Uncovering Beta-Lactam Susceptibility Patterns in Clinical Isolates of Mycobacterium tuberculosis through Whole-Genome Sequencing.

PMID 35695524 · 2022

The study identifies several genes and mutations associated with beta-lactam susceptibility in Mycobacterium tuberculosis, highlighting the role of specific genetic variations in influencing resistance patterns.

Gene Information

Gene Name: rpfC
Allele: rpfC
Encodes: Resuscitation-promoting factor C
Source Database: Reslit
Mechanism: confers resistance to beta-lactams
Confers Resistance To: AmoxicillinMeropenem
Organisms Tested In: • Mycobacterium tuberculosis
Geographic Location: Portugal
Validation Method: core-SNV analysis and MIC testing
Sequence Accession: NCBI BioProject PRJNA735825

Browse AMR Genes

rpfC

Mutations

Gene Information