Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
ribosomal protein L22
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| K90W | - | - | Escherichia coli | erythromycin | Reslit | Candidate |
| K90F | - | - | Escherichia coli | erythromycin | Reslit | Candidate |
| K90L | - | - | Escherichia coli | erythromycin | Reslit | Candidate |
| K90P | - | - | Escherichia coli | erythromycintylosin | Reslit | Candidate |
| A84D | - | 50S ribosomal protein L22 | Campylobacter jejuni, Campylobacter coli | erythromycinmacrolides | Reference Gene CatalogReslit | Confirmed |
| G86E | - | 50S ribosomal protein L22 | Campylobacter jejuni, Campylobacter coli | erythromycinmacrolides | Reference Gene CatalogReslit | Confirmed |
| G86V | - | 50S ribosomal protein L22 | Campylobacter jejuni, Campylobacter coli | erythromycinmacrolides | Reference Gene CatalogReslit | Confirmed |
| A88E | - | 50S ribosomal protein L22 | Campylobacter jejuni, Campylobacter coli | erythromycinmacrolides | Reference Gene CatalogReslit | Confirmed |
| G52S | - | - | Chlamydia trachomatis | macrolidesazithromycin | Reslit | Candidate |
| R65C | - | - | Chlamydia trachomatis | macrolidesazithromycin | Reslit | Candidate |
| V77A | - | - | Chlamydia trachomatis | macrolidesazithromycin | Reslit | Candidate |
| G114D | - | - | Rhodothermus marinus | erythromycin | Reslit | Candidate |
| R9C | - | - | Bartonella bacilliformis | azithromycin | Reslit | Candidate |
| P87L | - | - | - | erythromycinazithromycin | Reslit | Candidate |
| K90M | - | - | - | erythromycinazithromycin | Reslit | Candidate |
| G91D | - | - | - | erythromycinazithromycin | Reslit | Candidate |
| Q90H | - | - | Mycoplasma synoviae | macrolides | Reslit | Candidate |
| A101V | - | - | Staphylococcus aureus | erythromycin | Reslit | Candidate |
| P80S | - | - | Shigella dysenteriae, Shigella sonnei | azithromycin | Reslit | Candidate |
| T279C | - | - | Mycoplasma pneumoniae | macrolides | Reslit | Candidate |
| A430G | - | - | Mycoplasma pneumoniae | macrolides | Reslit | Candidate |
| A209T | - | - | Mycoplasma pneumoniae | macrolides | Reslit | Candidate |
| L46Q | - | - | Shigella sonnei | azithromycin | Reslit | Candidate |
| D219I | - | - | Staphylococcus epidermidis | linezolid | Reslit | Candidate |
| L220D | - | - | Staphylococcus epidermidis | linezolid | Reslit | Candidate |
| G218V | - | - | Staphylococcus epidermidis | linezolid | Reslit | Candidate |
| I39T | - | - | Streptococcus pneumoniae | erythromycinclindamycin | Reslit | Candidate |
| I65V | - | - | Campylobacter jejuni | erythromycin | Reslit | Candidate |
| A103V | - | 50S ribosomal protein L22 | Campylobacter jejuni, Campylobacter coli | erythromycinmacrolides | Reference Gene CatalogReslit | Confirmed |
| S109A | - | - | Campylobacter jejuni | erythromycin | Reslit | Candidate |
| G112D | - | - | Mycoplasma bovis | macrolides | Reslit | Candidate |
| 292 and 256dup | - | - | Campylobacter | macrolides | Reslit | Candidate |
| R85RARAR | - | 50S ribosomal protein L22 | Campylobacter coli, Campylobacter jejuni | erythromycintylosin | Reference Gene Catalog | Established |
| H97HTSH | - | 50S ribosomal protein L22 | Campylobacter coli, Campylobacter jejuni | erythromycintylosin | Reference Gene Catalog | Established |
| A103C | - | 50S ribosomal protein L22 | Campylobacter jejuni | erythromycin | Reference Gene Catalog | Established |
| S77T | - | 50S ribosomal protein L22 | Enterococcus faecium | linezolid | Reference Gene Catalog | Established |
| K83KKGPSLK | - | 50S ribosomal protein L22 | Neisseria meningitidis | azithromycin | Reference Gene Catalog | Established |
| K90KARAK | - | 50S ribosomal protein L22 | Neisseria meningitidis | azithromycin | Reference Gene Catalog | Established |
| - | - | Salmonella Typhi | azithromycin | Reslit | Candidate | |
| - | - | - | erythromycin | Reslit | Candidate | |
| - | - | Salmonella Typhi | azithromycin | Reslit | Candidate | |
| - | - | - | erythromycin | Reslit | Candidate | |
| - | - | - | erythromycin | Reslit | Candidate | |
| - | - | Staphylococcus aureus | linezolid | Reslit | Candidate |
Recombineering reveals a diverse collection of ribosomal proteins L4 and L22 that confer resistance to macrolide antibiotics.
Research Article
mutations in rplV confer macrolide resistance
Mutational and transcriptomic changes involved in the development of macrolide resistance in Campylobacter jejuni.
Research Article
Mutations in rplV (L22) are associated with macrolide resistance.
Antimicrobial Resistance in Chlamydia trachomatis: Mechanisms and Mutations
Review
Mutations in rplV are associated with macrolide resistance in C. trachomatis.
A Survey of Spontaneous Antibiotic-Resistant Mutants of the Halophilic, Thermophilic Bacterium Rhodothermus marinus.
Research Article
Mutations in rplV gene
Azithromycin alters the microbiome composition, function and resistome in women with Chlamydia trachomatis infections.
Research Article
Mutations in rplV gene associated with azithromycin resistance in C. trachomatis.
Development and characterisation of highly antibiotic resistant Bartonella bacilliformis mutants.
Research Article
Ribosomal Mutations Conferring Macrolide Resistance in Legionella pneumophila.
Research Article
Mutations in L22 ribosomal protein contribute to macrolide resistance.
Development of molecular assays for the rapid and cost-effective determination of fluoroquinolone, macrolide and lincosamide susceptibility of Mycoplasma synoviae isolates.
Research Article
De novo acquisition of antibiotic resistance in six species of bacteria.
Research Article
Virulence factors and mechanisms of antimicrobial resistance in Shigella strains from periurban areas of Lima (Peru).
Research Article
In vitro subminimum inhibitory concentrations of macrolide antibiotics induce macrolide resistance in Mycoplasma pneumoniae.
Research Article
Identification and characterization of Shigella with decreased susceptibility to azithromycin in the United States, 2005 to 2014.
Research Article
mutational
Genetic Diversification and Resistome of Coagulase-Negative Staphylococci from Nostrils of Healthy Dogs and Dog-Owners in La Rioja, Spain.
Research Article
Mobile elements and chromosomal changes associated with MLS resistance phenotypes of invasive pneumococci recovered in the United States.
Research Article
SVR-flaA typing of erythromycin- and ciprofloxacin-resistant Campylobacter jejuni strains isolated from poultry slaughterhouses in southern Brazil.
Research Article
Identification of Antimicrobial Resistance-Associated Genes through Whole Genome Sequencing of Mycoplasma bovis Isolates with Different Antimicrobial Resistances.
Research Article
Antibiotic Resistance in Bacteria-A Review.
Review
Transmission of dominant strains of Campylobacter jejuni and Campylobacter coli between farms and retail stores in Ecuador: Genetic diversity and antimicrobial resistance.
Research Article
Synergy between efflux pump CmeABC and modifications in ribosomal proteins L4 and L22 in conferring macrolide resistance in Campylobacter jejuni and Campylobacter coli.
Research Article
rplV
Emergence of optrA-Mediated Linezolid Resistance in Enterococcus faecium: A Molecular Investigation in a Tertiary Hospital of Southwest China from 2014-2018.
Research Article
rplV
Genomic Epidemiology of Gonococcal Resistance to Extended-Spectrum Cephalosporins, Macrolides, and Fluoroquinolones in the United States, 2000-2013.
Research Article
rplV
Azithromycin resistance mechanisms in typhoidal salmonellae in India: A 25 years analysis.
Research Article
Intrinsic and selected resistance to antibiotics binding the ribosome: analyses of Brucella 23S rrn, L4, L22, EF-Tu1, EF-Tu2, efflux and phylogenetic implications.
Research Article
Polymorphisms in rplV were identified but not correlated with antibiotic resistance.
Phenotypic and genotypic characterization of linezolid resistance and the effect of antibiotic combinations on methicillin-resistant Staphylococcus aureus clinical isolates.
Research Article