Browse AMR Genes

Explore antimicrobial resistance genes from the literature

rplY

Ribosomal protein L25

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to rplY

Browse AMR rules for rplY

Validation StatusCandidate

Overview

Validation Method: experimental validation through sequencing and MIC testing
Drug Classes: Azithromycin, Amikacin
Organisms: Neisseria gonorrhoeae, Pseudomonas aeruginosa
Papers: 3
Databases: Reslit
Mutations: 2

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
Q41L	-	-	Pseudomonas aeruginosa	Amikacin	Reslit	Candidate
L100P	-	-	-	Azithromycin	Reslit	Candidate

Papers3

1

Canary in the Coal Mine: How Resistance Surveillance in Commensals Could Help Curb the Spread of AMR in Pathogenic Neisseria.

PMID 36154280 · 2022

Gene Information

Gene Name: rplY
Allele: rplY
Encodes: Ribosomal protein L25
Source Database: Reslit
Confers Resistance To: Azithromycin
Organisms Tested In: • Neisseria gonorrhoeae
Validation Method: experimental validation through sequencing and MIC testing