rpmF

50S ribosomal protein L32

Validation StatusCandidate

Overview

Mechanism: macrolide and phenicol resistance
Validation Method: genome-wide association study
Drug Classes: Florfenicol, Gamithromycin, Tilmicosin, Tildipirosin, Tulathromycin, Tylosin, Erythromycin
Organisms: Mycoplasma bovis, Staphylococcus aureus
Geographic Location: North America
Papers: 2
Databases: Reslit
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
Q103H	-	-	Staphylococcus aureus	Erythromycin	Reslit	Candidate

Papers2

Genome-Wide Association Study of Nucleotide Variants Associated with Resistance to Nine Antimicrobials in Mycoplasma bovis.

PMID 35889084 · 2022

The study identified nucleotide variants (NVs) associated with resistance to nine antimicrobials in Mycoplasma bovis, including mutations in parC and gyrA for fluoroquinolone resistance, and various ribosomal protein genes for tetracycline, macrolide, and phenicol resistance.

Gene Information

Gene Name: rpmF
Allele: rpmF
Encodes: 50S ribosomal protein L32
Source Database: Reslit
Mechanism: macrolide and phenicol resistance
Confers Resistance To: FlorfenicolGamithromycinTilmicosinTildipirosinTulathromycinTylosin
Organisms Tested In: • Mycoplasma bovis
Geographic Location: North America
Validation Method: genome-wide association study
Sequence Accession: PRJNA642970|PRJNA708306|PRJNA785928

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rpmF

Mutations

Gene Information