Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
RNA polymerase subunit
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| D451N | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
| V183G | - | single resistance variant | Mycobacterium tuberculosis | rifampicin | Card DatabaseReslit | Confirmed |
| D253Y | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
| D190E | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
| T187A | - | single resistance variant | Mycobacterium tuberculosis | rifampicin | Card DatabaseReslit | Confirmed |
| P25R | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
| G31S | - | single resistance variant | Mycobacterium tuberculosis | rifampicin | Card DatabaseReslit | Confirmed |
| D102G | - | - | - | rifampicin | Reslit | Candidate |
| V183A | - | single resistance variant | Mycobacterium tuberculosis | rifampicin | Card Database | Established |
| - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
Genomic epidemiology analysis of extremely drug-resistant tuberculosis in Shanghai, China.
Research Article
Mutations in rpoA were observed in EDR-TB strains and linked to transmission clustering.
Characterization of rifampicin-resistant Mycobacterium tuberculosis in Khyber Pakhtunkhwa, Pakistan.
Research Article
Genomic characterization and epidemiology of Mycobacterium tuberculosis lineage 2 isolates from Kazakhstan.
Research Article
Longitudinal Outbreak of Multidrug-Resistant Tuberculosis in a Hospital Setting, Serbia.
Research Article
The Evolution and Transmission Dynamics of Multidrug-Resistant Tuberculosis in an Isolated High-Plateau Population of Tibet, China.
Research Article
RpoA Gly31Ser is a common rifampicin resistance mutation.
A precision overview of genomic resistance screening in Ecuadorian isolates of Mycobacterium tuberculosis using web-based bioinformatics tools.
Research Article
High fluoroquinolone resistance proportions among multidrug-resistant tuberculosis driven by dominant L2 Mycobacterium tuberculosis clones in the Mumbai Metropolitan Region.
Research Article
Mutation in rpoA is associated with rifampicin resistance.
Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase.
Research Article
Mycobacterium tuberculosis rpoA mutations confer resistance to rifampicin; CARD accession: CARD:3004999
Cross-sectional Whole-genome Sequencing and Epidemiological Study of Multidrug-resistant Mycobacterium tuberculosis in China.
Research Article