rsfS

ribosomal silencing factor

Validation StatusCandidate

Overview

Mechanism: colistin resistance
Validation Method: whole genome sequencing and growth rate measurement
Drug Classes: Colistin
Organisms: Acinetobacter baumannii
Papers: 1
Databases: Reslit

Papers1

The Effect of Colistin Resistance-Associated Mutations on the Fitness of Acinetobacter baumannii.

PMID 27847502 · 2016

The study identifies four novel putative colistin resistance genes (A1S_1983, hepA, A1S_3026, and rsfS) and confirms the role of pmrB, lpxC, lpxA, and lpxD mutations in colistin resistance in Acinetobacter baumannii. Compensatory mutations partially or completely restored the fitness of LPS-deficient mutants.

Gene Information

Gene Name: rsfS
Allele: rsfS
Encodes: ribosomal silencing factor
Source Database: Reslit
Mechanism: colistin resistance
Confers Resistance To: Colistin
Organisms Tested In: • Acinetobacter baumannii
Validation Method: whole genome sequencing and growth rate measurement
Sequence Accession: MDWH00000000|MDWJ00000000|MDWK00000000|MDWL00000000|MDWG00000000|MDWI00000000|MDWF00000000|MDWM00000000

Comments (0)

No comments yet. Be the first to comment!

Browse AMR Genes

rsfS

Gene Information