Browse AMR Genes

Explore antimicrobial resistance genes from the literature

sat1

streptothricin acetyltransferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to sat1

Browse AMR rules for sat1

Validation StatusSupported

Overview

Validation Method: PCR and sequencing
Drug Classes: Streptothricin, Streptomycin
Organisms: Proteus mirabilis, Escherichia coli, Piscirickettsia salmonis, Citrobacter diversus, Klebsiella pneumoniae, Shigella spp., Providencia spp., Klebsiella oxytoca
Geographic Location: Chile, Egypt, Oklahoma
Alleles: 2
Papers: 4
Databases: Reslit

Allele Variants2

Allele	Database	Papers	Drug Classes	Organisms	Countries	Years	Sequence Accession	Protein Accession
sat1	Reslit	3	Streptothricin, Streptomycin	Proteus mirabilis +7	Oklahoma, Chile, Egypt	2005, 2018, 2021	CP013819\|AJ250203\|GU570569\|AB453229	-
SAT1

Papers4

1

Molecular characterization of multidrug-resistant Proteus mirabilis isolates from retail meat products.

PMID 16013378 · 2005

The study identified several AMR genes including aadA1, aadB, aadA2, dhfr1, sat1, and blaTEM-1 in multidrug-resistant Proteus mirabilis isolates from retail meat products. Mutations in gyrA and parC were also linked to nalidixic acid resistance.

Gene Information

Gene Name: sat1
Allele: sat1
Encodes: streptothricin acetyltransferase
Source Database: Reslit
Confers Resistance To: Streptothricin
Organisms Tested In: • Proteus mirabilis
• Escherichia coli
Geographic Location: Oklahoma
Validation Method: PCR and sequencing

2

Isolation, Functional Characterization and Transmissibility of p3PS10, a Multidrug Resistance Plasmid of the Fish Pathogen Piscirickettsia salmonis.

PMID 29867834 · 2018

The study identifies and characterizes the multidrug resistance plasmid p3PS10 in Piscirickettsia salmonis, which carries genes conferring resistance to chloramphenicol (cat2), tetracyclines (tetA(t31)), aminoglycosides (aadA1, sat1), and sulfonamides (sul2).

Gene Information

Gene Name: sat1
Allele: sat1
Encodes: streptothricin acetyltransferase
Source Database: Reslit
Confers Resistance To: Streptomycin
Organisms Tested In: • Piscirickettsia salmonis
• Escherichia coli
Geographic Location: Chile
Validation Method: cloning in E. coli + MIC
Sequence Accession: CP013819|AJ250203|GU570569|AB453229

3

Molecular Analysis of Antimicrobial Resistance among Enterobacteriaceae Isolated from Diarrhoeic Calves in Egypt.

PMID 34201226 · 2021

The study identified multiple antimicrobial resistance genes, including blaTEM, floR, dfrA1, dfrA17, aadA1, aadA2, aadA5, catB3, sat1, and blaPse1, in Enterobacteriaceae isolates from diarrhoeic calves in Egypt. These genes confer resistance to various antibiotics such as ampicillin, tetracycline, chloramphenicol, and others.

Gene Information

Gene Name: sat1
Allele: sat1
Encodes: Streptothricin acetyltransferase
Source Database: Reslit
Confers Resistance To: Streptothricin
Organisms Tested In: • Escherichia coli
• Citrobacter diversus
• Klebsiella pneumoniae
• Shigella spp.
• Providencia spp.
• Klebsiella oxytoca
Geographic Location: Egypt
Validation Method: DNA sequencing

4

A metabolomics pipeline highlights microbial metabolism in bloodstream infections.

PMID 38885650 · 2024

The study identifies SpeG and PA1472 as polyamine N-acetyltransferases in E. coli and P. aeruginosa, respectively, which affect bacterial membrane permeability and antibiotic susceptibility.

Gene Information

Gene Name: sat1
Allele: SAT1
Encodes: spermidine/spermine N1-acetyltransferase
Source Database: Reslit
Organisms Tested In: • Escherichia coli
Validation Method: cloning in E. coli + enzyme assays
Sequence Accession: NCBI:WP_011401234|NCBI:WP_011401235|NCBI Accession 1|NCBI Accession 2