sgm

aminoglycoside resistance methylase

Validation StatusCandidate

Overview

Validation Method: cloning and expression in various hosts
Drug Classes: sisomicin, gentamicin
Organisms: Micromonospora zionensis, Streptomyces lividans, Micromonospora melanosporea, Escherichia coli
Papers: 1
Databases: Reslit

Papers1

Cloning and characterization of an aminoglycoside resistance determinant from Micromonospora zionensis.

PMID 1447159 · 1992

The sgm gene from Micromonospora zionensis was cloned and characterized as an aminoglycoside resistance determinant, conferring resistance to sisomicin and gentamicin.

Gene Information

Gene Name: sgm
Allele: sgm
Encodes: aminoglycoside resistance methylase
Source Database: Reslit
Confers Resistance To: sisomicingentamicin
Organisms Tested In: • Micromonospora zionensis
• Streptomyces lividans
• Micromonospora melanosporea
• Escherichia coli
Validation Method: cloning and expression in various hosts
Sequence Accession: PMC207509

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